Authors :
Laxman Andge; Vaishnavi Gabhane; Akash Ande
Volume/Issue :
Volume 9 - 2024, Issue 2 - February
Google Scholar :
http://tinyurl.com/mp3vxb4p
Scribd :
http://tinyurl.com/yu3t3zyt
DOI :
https://doi.org/10.5281/zenodo.10686866
Abstract :
Vitiligo is an autoimmune disorder or
inflammatory condition associated with itchy, scaly skin
& disfiguring skin lesion. Numerous studies on natural
products with anti-psoriatic action have been conducted
as a result of the lack of treatment options and
accompanying drawbacks in allopathic therapy. Nigella
sativa (Black cumin), Ocimum sanctum (Tulsileaves),
GlycyrrhizaGlabra (Liquorice), Curcuma longa
(Turmericrhizomes) was found to be efficacious and
cheap anti-inflammatory and immuno modulator drugs
with least in comparison to synthetic medications used to
cure vitiligo, negative effects. These medications were
chosen for the current investigation since the objective
was to produce a herbal cream for use in vitiligo skin
repigmentation therapy. A polyherbal cream design and
development attempt was produced taking into account
the aforementioned justification. Different crude drugs
extracts were taken &polyherbal cream was prepared.
Accelerated stability testing of three sample has been
conducted in the environmental chamber with
temperature 25 ± 100C and humidity 60 ± 10% RH. The
“F1” formulation were found to be stable with no sign of
phase separation and no change in the colour. The
sensitivity test patch has also been used, and there has
been no indication of skin irritability or allergy
symptoms.
Keywords :
Vitiligo, Polyherbal Cream, Synthetic chemical, Cosmeceutical, Repigmentation
Vitiligo is an autoimmune disorder or
inflammatory condition associated with itchy, scaly skin
& disfiguring skin lesion. Numerous studies on natural
products with anti-psoriatic action have been conducted
as a result of the lack of treatment options and
accompanying drawbacks in allopathic therapy. Nigella
sativa (Black cumin), Ocimum sanctum (Tulsileaves),
GlycyrrhizaGlabra (Liquorice), Curcuma longa
(Turmericrhizomes) was found to be efficacious and
cheap anti-inflammatory and immuno modulator drugs
with least in comparison to synthetic medications used to
cure vitiligo, negative effects. These medications were
chosen for the current investigation since the objective
was to produce a herbal cream for use in vitiligo skin
repigmentation therapy. A polyherbal cream design and
development attempt was produced taking into account
the aforementioned justification. Different crude drugs
extracts were taken &polyherbal cream was prepared.
Accelerated stability testing of three sample has been
conducted in the environmental chamber with
temperature 25 ± 100C and humidity 60 ± 10% RH. The
“F1” formulation were found to be stable with no sign of
phase separation and no change in the colour. The
sensitivity test patch has also been used, and there has
been no indication of skin irritability or allergy
symptoms.
Keywords :
Vitiligo, Polyherbal Cream, Synthetic chemical, Cosmeceutical, Repigmentation
