Denture stomatitis is a common oral lesion seen with the use in patients using removable dentures (65%). Candida Albicans is known to be one of the major factor that causes this apart from the other commonly known factors. Denture stomatitis can be treated in several ways which may include using topical and systemic antifungal agents, cleansing agents to clean the denture, disinfection procedure, replacement of old and worn out denture, denture relining, reestablishment of atraumatic occlusion and nutritional restitution. Denture relining materials are materials that act like shock absorbers where the lessen the force passed on to the tissues. Resilient liners degrade quite easily and also are susceptible to colonization by microbes which may cause different levels of denture stomatitis . Also rapid loss of viscoelasticity following clinical use due to leaching of plasticizer into the oral environment is observed. Hence frequent clinical evaluation and periodic replacement of the soft liners is required. Antifungal agents can be incorporated to increase the clinical longevity of these materials and also to reduce the microbial accumulation. Denture liners modified by antifungal agents at commercially available concentrations may affect their physical properties, which may impair the clinical performance of these materials. Also, another factor that may affect the longevity is the duration of the bond Therefore, this study evaluates the tensile bond strengths of denture liners modified by antifungal agents to the denture base resin. Purpose:To evaluate and compare the tensile bond strength between denture base resin to two different denture liners altered by the incorporation of antifungal agents. Methodology: Sixty six samples were divided into 6 groups (2 control groups and 4 test groups) containing 11 samples each, Each sample should contained 2 acrylic plates of dimension (20x20x4mm) and these acrylic plates were kept for 30 days at 37 degrees Celsius in distilled water. Acrylic plate on which the liner was to be applied was sandblasted using the korox 110 powder to create surface irregularities. The stainless steel square split spacer was placed over the first acrylic plate .6.35gdenture liner powder will be blended uniformly with the specified amount of antifungal powder followed by mixing the denture liner liquid(5ml) to according to instructions specified by the manufacturer. The denture liner was injected into the hollow stainless steel square split spacer to overfill. The second acrylic plate was sandblasted to create surface irregularities before placing it over the syringed liner material and any flash of excess denture liner will be removed using a sharp surgical blade. A Weight of 5kg is placed over the second acrylic plate and the liner material was allowed to set. The specimens were kept in distilled water again for 24hours at 37˚c before testing is done. The specimens were subjected to the testing by the universal testing machine. Results: At the end of the testing, the results revealed that both the liner materials showed no significant differences in their tensile bond strength of addition of fluconazole antifungal agent but significant differences were seen in the tensile bond strength with the denture base resin on addition of miconazole antifungal agent. Keywords—Denture liners, Resilient liners, Antifungal agents, Tensile bond strength