The study is to focus at the evaluation of the
potential of the antibacterial activity of the synthesized
Zinc oxide nanoparticle using Leptadenia hastata leaf
extracts on selected bacterial; E.coli, S. aureus, K.
pneumonia. Zinc oxide (ZnO) nanoparticles synthesised,
UV, SEM and FTIR were used to characterise the
nanoparticles. The particles were further subjected to
evaluation of their antimicrobial activity. The FTIR
studies was observed to have shown the several
chemical functional groups, while the SEM results
showed the synthesized nanoparticles were in the range
below 100 nm and the size of the particles was slightly
ellipsoidal as well as spherical. From the result it was
observed that the synthesised nanoparticles have
showed significant antimicrobial potentials against the
gram negative and gram positive bacteria’s (E. Coli, S.
aureus and K. Pneumonia. This study being the first
using Leptadenia hastata leaf extract should provide a
new agent toward the fight of resistance bacterial and
effective therapies in the field of medicine.
Keywords : Biosynthesis, Zinc oxide, nanoparticles, Leptadenia hastata, leaf, antimicrobial, characterization.