Authors : Dr. Bharti Vyas; Dr. Ramkishore Ratre; Dr. Sandhya Jain; Dr. Vijay Bhan Singh; Dr. U R Neelima; Dr. Yojna Atram

Volume/Issue : Volume 10 - 2025, Issue 5 - May

Google Scholar : https://tinyurl.com/mreakscj

DOI : https://doi.org/10.38124/ijisrt/25may1026

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

Abstract : White spot lesions (WSLs) represent subsurface demineralization of enamel which possess a significant challenge in orthodontics due to their prevalence and potential to progress. The recent studies from past decade were searched in electronic databases including Pubmed, Scopus and google scholar involving white spot lesions and effect of orthodontic treatment. The review evaluates the current state of knowledge regarding the etiology, diagnosis, and management of WSLs, with a specific focus on remineralizing agents. Diagnostic modalities are discussed in the context of their utility for early detection and monitoring of WSLs. Remineralization therapies utilizing fluoride, calcium phosphate- based compounds like anticay, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) complexes, and bioactive glasses, are reviewed for their efficacy in promoting remineralization and inhibiting demineralization. Furthermore, clinical studies evaluating the effectiveness of remineralization therapies are critically analyzed, with an emphasis on their outcomes in terms of lesion remineralization, surface hardness, and long-term stability of remineralized tissues. Additionally, novel approaches, including nanotechnology-based delivery systems and biomimetic strategies, are highlighted as avenues for future research and development.

Keywords : White Spot Lesions, Orthodontic Treatment, Enamel Dimineralization.

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