Authors :
Hala Hassan Deeb
Volume/Issue :
Volume 9 - 2024, Issue 6 - June
Google Scholar :
https://tinyurl.com/j655bwj9
Scribd :
https://tinyurl.com/px39bf9y
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24JUN1396
Abstract :
Vit D deficiency is a public health problem
worldwide. According to epidemiological studies, low Vit
D levels have been associated with an increased risk of
certain neurodevelopmental disorders, including autism
spectrum disorder, but the risk of high concentration of
Vit D is not clearly affect in nervous system.. In this
research, we studied whether vitamin D concentrations
were associated with the activity of the nervous system in
healthy people by comparing catecholamines
concentrations in blood of 42 healthy women (age = 40-50
years old, body mass index: 22.7 ± 2.1 kg/m2). We had
three groups as Vit D levels: (Deficient: vit D: ≤ 20 ng/L),
(insufficient vita D 20-29 ng/L), (Sufficient vit D: ≥30≤70
ng/L). In our study:_ Plasma Noradrenaline decreased
statistically significant ( p˂0.005) in high levels of vit D, _
Plasma Adrenaline increased statistically significant (
p˂0.005) in high levels of vit D,_ Plasma Dopamine
increased statistically significant only in high levels of
vitamin D. It should be mentioned that high levels of vita
D has also been related to mood disorders, movement and
a Calcium status. There was a statistical association
between several measures of nervous system, hormones
activity and vita D levels. This suggests that vita D induces
catecholamine synthesis and/or secretion.
Keywords :
Adrenaline, Dopamine, Catecholamines, MAO, Vitamin D.
References :
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Vit D deficiency is a public health problem
worldwide. According to epidemiological studies, low Vit
D levels have been associated with an increased risk of
certain neurodevelopmental disorders, including autism
spectrum disorder, but the risk of high concentration of
Vit D is not clearly affect in nervous system.. In this
research, we studied whether vitamin D concentrations
were associated with the activity of the nervous system in
healthy people by comparing catecholamines
concentrations in blood of 42 healthy women (age = 40-50
years old, body mass index: 22.7 ± 2.1 kg/m2). We had
three groups as Vit D levels: (Deficient: vit D: ≤ 20 ng/L),
(insufficient vita D 20-29 ng/L), (Sufficient vit D: ≥30≤70
ng/L). In our study:_ Plasma Noradrenaline decreased
statistically significant ( p˂0.005) in high levels of vit D, _
Plasma Adrenaline increased statistically significant (
p˂0.005) in high levels of vit D,_ Plasma Dopamine
increased statistically significant only in high levels of
vitamin D. It should be mentioned that high levels of vita
D has also been related to mood disorders, movement and
a Calcium status. There was a statistical association
between several measures of nervous system, hormones
activity and vita D levels. This suggests that vita D induces
catecholamine synthesis and/or secretion.
Keywords :
Adrenaline, Dopamine, Catecholamines, MAO, Vitamin D.