The biologically active form of vitamin D, 1,25
dihydroxy vitamin D (1,25(OH)2D), and its receptor,
vitamin D receptor (VDR), play critical roles in oral
immunity and periodontal health. Vitamin D is essential
for a range of organ systems; yet, shortage is common,
with 30 to 50 percent of the population suffering from it.
Vitamin D insufficiency has been linked to not just low
mineral bone density/osteoporosis and osteopenia, but
also infectious and chronic inflammatory illnesses,
according to research. Vitamin D has been linked to
periodontal disease due to its effects on bone and mineral
metabolism, innate immunity, and various vitamin D
receptor gene polymorphisms.
Keywords : Periodontal disease, Vitamin D receptor gene polymorphism, Vitamin D.