Guillain Barré syndrome (GBS),is an autoimmune neurological disease. A patient with history of GBSmay present as a challenge for the anaesthesiologist, due to the possibility of impairment of neuromuscular function and occurrence of respiratory complications in the postoperative period. Case report: We are reporting here the anaesthetic management of a 29 year old female patientwith 8 months of amenorrhea with premature rupture of membranes having history of Guillain Barre syndrome posted for Emergency Caesarean section. We have discussed here the intraoperative management and mode of anaesthesia for such a patient. Conclusion: Anaesthesiologist rarely may encounter such patients in regular practice, so it is important to understand the peculiarities of GBS to adequately manage the patient in the perioperative period.