EHRs facilitate sharing of healthcare from clinicians involved in patient care within and across health facilities. Interoperable EHRs can facilitate this exchange of information and as a result be able to facilitate decision making. Despite increasing adoption of EHRs in Tanzania, the realization of benefits that EHRs could offer through interoperability still lags behind. Currently most EHRs are not interoperable thus making it difficult to facilitate exchange of information between systems. The aim of the study therefore was to contribute to final conceptual frameworks that relate Interoperability and Decision making in the healthcare. Integrated Literature review was conducted to understand concepts related to Interoperability and decision making. Six propositions emerged from relevant studies that contribute in understanding the role of EHRs interoperability in facilitating decision making. Interoperability allows for collaboration which is an important aspect in decision making. Several studies have identified the benefits of having interoperable EHRs, but few have explored on how such benefits can contribute on decision-making

Keywords : EHRs Interoperability; Decision Making; Electronic Health Records Systems; Decision Support.