Authors :
Sri Rahmi Utami; Suhatri; Yelly Oktavia Sari
Volume/Issue :
Volume 7 - 2022, Issue 5 - May
Google Scholar :
https://bit.ly/3IIfn9N
Scribd :
https://bit.ly/3zCruEt
DOI :
https://doi.org/10.5281/zenodo.6648075
Abstract :
This Stroke is the third leading cause of death
globally after cardiovascular disease and cancer. The
highest death rate in Indonesia is caused by stroke
(21.2%), and data from the Indonesian Ministry of Health
reports that stroke is the highest cause of death in
Indonesia, which is 51%. Stroke patients who are
hospitalized generally experience drug- related problems
(DRPs), especially patients with complications and
comorbidities. This study aims to determine the types of
DRPs and the relationship between DRPs and Clinical
Outcomes in ischemic stroke patients in the inpatient
neurology ward of RSUP Dr. M. Djamil Padang. This
study is an observational study using a descriptive crosssectional design, conducted by collecting data on ischemic
stroke patients prospectively during the period May –
July 2019. Data analysis used statistics using parametric
test methods (T- Test and One Way Annova) and nonparametric test methods (Mann U Whitney and Kruskal
Wallis Test). It was found that the most used drugs in
stroke patients were antihypertensive drugs; amlodipine
(class Ca Chanel Blocker) and candesartan (class
Angiotensin Receptor Blocker), antiplatelet drugs;
aspirin, H2 antagonist drugs; ranitidine, an antibacterial
drug; ceftriaxone, a mucolytic drug; N – acetylcysteine
and body fluids; stranger. For the types of Drug-Related
Problems, namely drugs without indications at 14.29%,
indications that are not treated by 59.52%, inappropriate
drug selection by 16.47 %, excess doses by 0%, under
doses by 2.38%, side effect reactions are 0%, drug
interactions are 7.14%, and failure to receive drugs is 0%.
From the results of statistical tests, it was found that there
was a relationship between Drug- Related Problems in the
inappropriate drug category and drug interactions with
Clinical Outcomes of patients with systolic blood
pressure. Then, there was a relationship between DrugRelated Problems in the category of drugs without the
Clinical Outcomes score of patients with the Glasgow
Coma Scale.
Keywords :
Clinical Outcomes; DRPs; Ischemic Stroke; Ischemic Stroke Therapy).
This Stroke is the third leading cause of death
globally after cardiovascular disease and cancer. The
highest death rate in Indonesia is caused by stroke
(21.2%), and data from the Indonesian Ministry of Health
reports that stroke is the highest cause of death in
Indonesia, which is 51%. Stroke patients who are
hospitalized generally experience drug- related problems
(DRPs), especially patients with complications and
comorbidities. This study aims to determine the types of
DRPs and the relationship between DRPs and Clinical
Outcomes in ischemic stroke patients in the inpatient
neurology ward of RSUP Dr. M. Djamil Padang. This
study is an observational study using a descriptive crosssectional design, conducted by collecting data on ischemic
stroke patients prospectively during the period May –
July 2019. Data analysis used statistics using parametric
test methods (T- Test and One Way Annova) and nonparametric test methods (Mann U Whitney and Kruskal
Wallis Test). It was found that the most used drugs in
stroke patients were antihypertensive drugs; amlodipine
(class Ca Chanel Blocker) and candesartan (class
Angiotensin Receptor Blocker), antiplatelet drugs;
aspirin, H2 antagonist drugs; ranitidine, an antibacterial
drug; ceftriaxone, a mucolytic drug; N – acetylcysteine
and body fluids; stranger. For the types of Drug-Related
Problems, namely drugs without indications at 14.29%,
indications that are not treated by 59.52%, inappropriate
drug selection by 16.47 %, excess doses by 0%, under
doses by 2.38%, side effect reactions are 0%, drug
interactions are 7.14%, and failure to receive drugs is 0%.
From the results of statistical tests, it was found that there
was a relationship between Drug- Related Problems in the
inappropriate drug category and drug interactions with
Clinical Outcomes of patients with systolic blood
pressure. Then, there was a relationship between DrugRelated Problems in the category of drugs without the
Clinical Outcomes score of patients with the Glasgow
Coma Scale.
Keywords :
Clinical Outcomes; DRPs; Ischemic Stroke; Ischemic Stroke Therapy).
