Drug addiction is defined by an uncontrollable and persistent desire to seek and consume the drug. Due to developments in the understanding of mechanisms involved as well as the need for more precision in definition, drug nomenclature has developed over time. Drug addiction is caused by how drugs of consumption interact with each individual's neurobehavioral constitution, as well as their pharmacological consequences. The study of the neural molecular mechanisms addiction processes allows for a better understanding of current pharmacotherapy as well as the development of novel drug misuse and dependency treatment options. In this work, we want to present recent ideas about abuse and addiction.