Dysmenorrhea is the most common problem in women of childbearing age. Treatment for dysmenorrhea includes NSID, OCP, COX-2 specific inhibitors, but due to side effects, the majority of women prefer to use complementary alternative medicine. Objective: This study aimed to analyze the effect of vitamin D therapy on the level and duration of primary dysmenorrhea pain in women of childbearing age. Method: Search articles through Science Direct, PubMed, and Pro-Quest databases using boolean operators (AND and OR). The study inclusion criteria were publication in English, study design Randomized Controlled Trial from 2015 to 2021, female study participants with primary dysmenorrhea, ages 18 to 49 years, intervention given was vitamin D compared with placebo, or in combination with mefenamic acid., novafen and calcium carbonate. The results of the level and duration of pain were measured by VAS (Visual Analog Scale). Results: Statistical tests showed a significant change in pain intensity after administration of vitamin D therapy, which is where the administration of vitamin D can affect the pain of dysmenorrhea. Conclusion: Vitamin D therapy can be considered to treat primary dysmenorrhea.

Keywords : Dysmenorrhea, Vitamin D, Pain Level, Pain Duration, Randomized Controlled Trial.