This study took for comparing efficacy of
IV Dexmedetomidine 0.5µg/kg and IV Dexmedetomidine
1µg /kg in obtunding the hemodynamic response to
laryngoscopy and endotracheal intubation when
administered 10 minutes before induction.
Methodology: A Ninety patients scheduled for various
elective and emergency surgical procedures under
general anesthesia belonging to ASA class I & II and
Mallampati grade I & II in the age group of 18 years to
60 years were included in the study.
The study population was randomly divided into three
groups group A received normal saline and represent as
control , group B received IV Dexmedetomidine in a dose
of 0.5µg/kg, group C received IV Dexmedetomidine in a
dose of 1µg/kg
The HR, SBP, DBP and MAP were recorded at the
following intervals, namely, basal reading before giving
the study drug, at 5 minute intervals from the end of drug
infusion until induction, post induction/ prelaryngoscopy and at 1, 2.5, 5, 10, 15 and 20 minutes
following tracheal intubation.
Dexmedetomidine, Hemodynamic Response.