The Effect of Intravenously Administered Dexmedetomidine on Haemodynamic Response to Intubation in Patients Undergoing Surgery Under General Anaesthesia


Authors : Dr.K.Yashaswi Srivasthava; Dr. Y. V. Somashekar

Volume/Issue : Volume 8 - 2023, Issue 1 - January

Google Scholar : https://bit.ly/3IIfn9N

Scribd : https://bit.ly/3J1b4tX

DOI : https://doi.org/10.5281/zenodo.7558011

Abstract : This study took for comparing efficacy of IV Dexmedetomidine 0.5µg/kg and IV Dexmedetomidine 1µg /kg in obtunding the hemodynamic response to laryngoscopy and endotracheal intubation when administered 10 minutes before induction. Methodology: A Ninety patients scheduled for various elective and emergency surgical procedures under general anesthesia belonging to ASA class I & II and Mallampati grade I & II in the age group of 18 years to 60 years were included in the study. The study population was randomly divided into three groups group A received normal saline and represent as control , group B received IV Dexmedetomidine in a dose of 0.5µg/kg, group C received IV Dexmedetomidine in a dose of 1µg/kg The HR, SBP, DBP and MAP were recorded at the following intervals, namely, basal reading before giving the study drug, at 5 minute intervals from the end of drug infusion until induction, post induction/ prelaryngoscopy and at 1, 2.5, 5, 10, 15 and 20 minutes following tracheal intubation.

Keywords : Dexmedetomidine, Hemodynamic Response.

This study took for comparing efficacy of IV Dexmedetomidine 0.5µg/kg and IV Dexmedetomidine 1µg /kg in obtunding the hemodynamic response to laryngoscopy and endotracheal intubation when administered 10 minutes before induction. Methodology: A Ninety patients scheduled for various elective and emergency surgical procedures under general anesthesia belonging to ASA class I & II and Mallampati grade I & II in the age group of 18 years to 60 years were included in the study. The study population was randomly divided into three groups group A received normal saline and represent as control , group B received IV Dexmedetomidine in a dose of 0.5µg/kg, group C received IV Dexmedetomidine in a dose of 1µg/kg The HR, SBP, DBP and MAP were recorded at the following intervals, namely, basal reading before giving the study drug, at 5 minute intervals from the end of drug infusion until induction, post induction/ prelaryngoscopy and at 1, 2.5, 5, 10, 15 and 20 minutes following tracheal intubation.

Keywords : Dexmedetomidine, Hemodynamic Response.

Never miss an update from Papermashup

Get notified about the latest tutorials and downloads.

Subscribe by Email

Get alerts directly into your inbox after each post and stay updated.
Subscribe
OR

Subscribe by RSS

Add our RSS to your feedreader to get regular updates from us.
Subscribe