Schizophrenia is a chronic, severe, and disabling disease, a brain disorder characterized by chaotic thoughts, delusions, hallucinations, and strange or catatonic behavior. Adherence to taking medication in schizophrenic patients can be detected using the Medication Adherence Rating Scale (MARS). This study aims to determine the description of compliance in taking medicine of schizophrenic clients in the Regional Mental Hospital of Jambi Province. This research uses descriptive design. The results showed that 112 (100%) had never been careless about the time to take medication when they felt it was better not to stop taking medication and not to take medication only when they were sick. A total of 110 (98.2%), if they felt worse when taking drugs did not stop taking medication, 81 (72.3%) could not for the mind and body to be controlled by medication, 99 (88.4%) his mind was not clear after taking medicine, 98 (87.5%) felt strange like zombies on medication, 71 (63.4%) never forgot to take medication and 64 (57.1%) drugs did not make respondents feeling tired and sluggish . Nurses should motivate schizophrenia clients to comply with taking medication.

Keywords : Schizophrenia, Adherence.