Authors :
M. Guezar; S. Khalf; K. Oulabbes; S. Badja; D. Kamal; F.Z. Farhane; Z. Alami; T. Bouhafa; MN. El Alami Elamine; K. Hassouni
Volume/Issue :
Volume 6 - 2021, Issue 4 - April
Google Scholar :
http://bitly.ws/9nMw
Scribd :
https://bit.ly/3gwD1LK
Abstract :
The multiple primary head and neck cancers
are becoming more frequent and are the cause of many
diagnostic and therapeutic difficulties . Synchronous
Nasopharyngeal carcinoma (NPC) and squamous cell
carcinoma of the lip (SCCL) is a rare case presentation to
be reported in literature.
We report a rare case of synchronous presentation of
NPC and SCC of the lip in a 44-years-old male patient
with a history of ultraviolet radiation exposure , a poor
oral hygiene and poor dietary habits. The patient first
presented with a diagnosis of squamous cell carcinoma of
the lower lip, the radiological assessment revealed a
thickening of the posterior wall of the cavum
corresponding of a nasopharyngeal carcinoma that was
confirmed by biopsy with histopathological examination.
The management consisted of surgical excision of the lip
tumor with reconstruction of substance loss and adjuvant
external radiotherapy to the tumor bed with concomitant
chemoradiotherapy for nasopharyngeal carcinoma with a
follow up of 24 months, without local relapse or remote
metastases.
Keywords :
Synchronous Carcinoma, Head and Neck Multiple Cancers, Epstein Barr Virus, Field Cancerization.
The multiple primary head and neck cancers
are becoming more frequent and are the cause of many
diagnostic and therapeutic difficulties . Synchronous
Nasopharyngeal carcinoma (NPC) and squamous cell
carcinoma of the lip (SCCL) is a rare case presentation to
be reported in literature.
We report a rare case of synchronous presentation of
NPC and SCC of the lip in a 44-years-old male patient
with a history of ultraviolet radiation exposure , a poor
oral hygiene and poor dietary habits. The patient first
presented with a diagnosis of squamous cell carcinoma of
the lower lip, the radiological assessment revealed a
thickening of the posterior wall of the cavum
corresponding of a nasopharyngeal carcinoma that was
confirmed by biopsy with histopathological examination.
The management consisted of surgical excision of the lip
tumor with reconstruction of substance loss and adjuvant
external radiotherapy to the tumor bed with concomitant
chemoradiotherapy for nasopharyngeal carcinoma with a
follow up of 24 months, without local relapse or remote
metastases.
Keywords :
Synchronous Carcinoma, Head and Neck Multiple Cancers, Epstein Barr Virus, Field Cancerization.
