Diabetes mellitus is a metabolic disorder associated with chronic hyperglycemia caused by inherited or acquired deficiency of insulin production or resistance to action of the produced insulin. In the present study fresh leaves extracts of Azadirachta indica, Bryophyllum pinnatum, Carica papayaand Mikania cordatawere selected on the basis of traditional behavior of local people for the treatment of diabetes in Bangladesh. Crude extracts prepared by aqueous UAE method was used in this study on hormone induced diabetic mice by FPG Test. Most of the plants showed marked anti-diabetic properties comparison to the standard antidiabetic drug Glibenclamide.

Keywords : Diabetes, Glucocorticoid, Dexamethasone, FPG, Ultrasound