The Prevalence of G6PD Deficiency and its Associated Factors Among the National University Students in the Middle Province (Ibb City), Yemen


Authors : Abdullah Abdulgabber Ahmed Al-alimi; Abdullah Abdulgabber Ahmed Al-alimi; Amen Faisal Ahmed Albaadani

Volume/Issue : 2nd ICTSA-2022

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://bit.ly/40BSZbl

DOI : https://doi.org/10.5281/zenodo.7773214

Glucose 6 phosphate dehydrogenase (G6PD) is a critical an enzyme for protecting erythrocytes from oxidative stress and hemolysis. G6PD deficiency is a significant public health problem in the world countries and it is associated with hemolytic complications in individuals exposed to internal and external oxidative stress. The present study aimed to determine the prevalence of G6PD deficiency and its associated factors among university students from different indigenous areas in Ibb city. A cross-sectional study recruited randomly on 200 students (150 males & 50 females) whose decedent from different areas in Ibb province. 3ml of blood samples were collected to quantify G6PD activity levels and complete cell count (CBC) and questionnaire apply to collected history symptoms of hemolytic anemia and socio-demographic information. Twenty three (19 males and 4 females) students were have G6PD deficiency with overall prevalence rate was 11.5% (9.5 % in males & 2.0% in females). G6PD deficient students having low significant (p<0.05) levels of Hb and RBCs count compared to normal G6PD students. 56% of G6PD deficiency students had been residing in Al-dihar place compared to 35% residing in AL-mashanah and 9% residing in other places with odd deficiency no significant (OR=1.7; 95%CI 0.8-5.0, p=0.44). 78 % of G6PD deficient students were having parents consanguineous marriage with a higher odd (OR=5.0; 95% CI 2-13, p=0.002). 70% (OR=11.0; 95% CI 4.4-30.9, p<0.0001) and 17% (OR=5.1; 95%CI 1.4-19,

Keywords : Glucose-6-Phosphate Dehydrogenase (G6PD), G6PD Deficiency, Episodes, Hemolytic Anemia, Risk factors, Students, University, Ibb, Yemen

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