Authors : Abdullah Abdulgabber Ahmed Al-alimi; Abdullah Abdulgabber Ahmed Al-alimi; Amen Faisal Ahmed Albaadani
Volume/Issue : 2nd ICTSA-2022
Google Scholar : https://bit.ly/3TmGbDi
Scribd : https://bit.ly/40BSZbl
DOI : https://doi.org/10.5281/zenodo.7773214
Glucose 6 phosphate dehydrogenase (G6PD) is a
critical an enzyme for protecting erythrocytes from
oxidative stress and hemolysis. G6PD deficiency is a
significant public health problem in the world countries
and it is associated with hemolytic complications in
individuals exposed to internal and external oxidative
stress. The present study aimed to determine the
prevalence of G6PD deficiency and its associated factors
among university students from different indigenous
areas in Ibb city.
A cross-sectional study recruited randomly on 200
students (150 males & 50 females) whose decedent from
different areas in Ibb province. 3ml of blood samples
were collected to quantify G6PD activity levels and
complete cell count (CBC) and questionnaire apply to
collected history symptoms of hemolytic anemia and
socio-demographic information.
Twenty three (19 males and 4 females) students
were have G6PD deficiency with overall prevalence rate
was 11.5% (9.5 % in males & 2.0% in females). G6PD
deficient students having low significant (p<0.05) levels
of Hb and RBCs count compared to normal G6PD
students. 56% of G6PD deficiency students had been
residing in Al-dihar place compared to 35% residing in
AL-mashanah and 9% residing in other places with odd
deficiency no significant (OR=1.7; 95%CI 0.8-5.0,
p=0.44). 78 % of G6PD deficient students were having
parents consanguineous marriage with a higher odd
(OR=5.0; 95% CI 2-13, p=0.002). 70% (OR=11.0; 95%
CI 4.4-30.9, p<0.0001) and 17% (OR=5.1; 95%CI 1.4-19,
Keywords : Glucose-6-Phosphate Dehydrogenase (G6PD), G6PD Deficiency, Episodes, Hemolytic Anemia, Risk factors, Students, University, Ibb, Yemen