Authors : Daniel John Aban Your; Ahmed Hamad Alnory; Adel Ali Ahmed Mohammed

Volume/Issue : Volume 11 - 2026, Issue 5 - May

Google Scholar : https://tinyurl.com/2dkjxefx

Scribd : https://tinyurl.com/3bze4nvv

DOI : https://doi.org/10.38124/ijisrt/26may1520

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

Abstract : Cancer is an emerging public health and socioeconomic challenge in South Sudan, driven by the interaction of biological, social, cultural, and healthcare-related factors. The paper was conducted to determine the level and pattern of cancer and identify the major socio-demographic factors associated with cancer in South Sudan. The study reveals that increasing age, gender differences, hereditary factors, poverty, low education, cultural practices, occupational exposures, and weak healthcare infrastructure significantly influence cancer occurrence and progression. Women face elevated reproductive cancer risks linked to cervical, breast, and ovarian cancers, while men show higher overall cancer exposure due to hazardous occupations, smoking, alcohol use, and delayed healthcare-seeking behaviour. Rural populations and low-income groups experience limited access to screening, diagnosis, and treatment services, leading to late-stage diagnosis and poor survival outcomes. The findings further indicate that low awareness, limited preventive services, weak oncology systems, and ongoing conflict intensify the cancer burden. The study concludes that reducing cancer in South Sudan requires comprehensive strategies involving public awareness, HPV vaccination, early screening, improved reproductive health services, occupational safety measures, rural healthcare expansion, and strengthened diagnostic and oncology services.

Keywords : Cancer, Socio-Demographic, South Sudan.

References :

1. Barker, E. K., Malekinejad, M., Merai, R., Lyles, C. M., Sipe, T. A., DeLuca, J. B., ... and Kahn, J. G. (2022). Risk of human immunodeficiency virus acquisition among high-risk heterosexuals with nonviral sexually transmitted infections: a systematic review and meta-analysis. Sexually Transmitted Diseases, 49(6), 383-397.
2. Bayo, S., Bosch, F. X., de Sanjosé, S., Muñoz, N., Combita, A. L., Coursaget, P., ... and Meijer, C. J. (2002). Risk factors of invasive cervical cancer in Mali. International journal of epidemiology, 31(1), 202-209.
3. Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., and Jemal, A. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians, 68(6), 394-424.
4. Caubel, J. J. (2018). Solving the Air Pollution Crisis: Mitigation and Monitoring (Doctoral dissertation, University of California, Berkeley).
5. Cutler, D., Deaton, A., and Lleras-Muney, A. (2006). The determinants of mortality. Journal of economic perspectives, 20(3), 97-120.
6. De Flora, S., and Bonanni, P. (2011). The prevention of infection-associated cancers. Carcinogenesis, 32(6), 787-795.
7. de Sanjose, S., Almirall, R., Lloveras, B., Font, R., Diaz, M., Muñoz, N., ... and Bosch, F. X. (2003). Cervical human papillomavirus infection in the female population in Barcelona, Spain. Sexually transmitted diseases, 30(10), 788-793.
8. Diaz-Bonilla, C., and Sabatino, C. (2022). April 2022 Update to the Multidimensional Poverty Measure: What's New (No. 22). The World Bank.
9. Hall, J. M., Lee, M. K., Newman, B., Morrow, J. E., Anderson, L. A., Huey, B., and King, M. C. (1990). Linkage of early-onset familial breast cancer to chromosome 17q21. Science, 250(4988), 1684-1689.
10. MacMahon, B., Cole, P., Lin, T. M., Lowe, C. R., Mirra, A. P., Ravnihar, B., ... and Yuasa, S. (1970). Age at first birth and breast cancer risk—Bulletin of the World Health Organization, 43(2), 209.
11. Maggen, C., Wolters, V. E., Cardonick, E., Fumagalli, M., Halaska, M. J., Lok, C. A., ... and International Network on Cancer, Infertility and Pregnancy (INCIP). (2020). Pregnancy and cancer: the INCIP project. Current oncology reports, 22(2), 17.
12. Marmot, M. (2005). Status syndrome: How your social standing directly affects your health. A and C Black.
13. Miki, Y., Swensen, J., Shattuck-Eidens, D., Futreal, P. A., Harshman, K., Tavtigian, S., ... and Skolnick, M. H. (1994). A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science, 266(5182), 66-71.
14. Mwanje, J. (2023). Cervical cancer screening in resource-poor settings of South Sudan: access coverage, associated factors and health system interventions.
15. Ngwa, W., Addai, B. W., Adewole, I., Ainsworth, V., Alaro, J., Alatise, O. I., ... and Kerr, D. (2022). Cancer in sub-Saharan Africa: a Lancet Oncology Commission. The Lancet Oncology, 23(6), e251-e312.
16. Shah, S. C., Kayamba, V., Peek Jr, R. M., and Heimburger, D. (2019). Cancer control in low-and middle-income countries: is it time to consider screening?. Journal of global oncology, 5, 1-8.
17. Singh, G. K., and Jemal, A. (2017). Socioeconomic and racial/ethnic disparities in cancer mortality, incidence, and survival in the United States, 1950–2014: over six decades of changing patterns and widening inequalities. Journal of environmental and public health, 2017(1), 2819372.
18. Stefanek, M. E., Andrykowski, M. A., Lerman, C., Manne, S., Glanz, K., and AACR Behavioural Science Task Force. (2009). Behavioural oncology and the war on cancer: Partnering with biomedicine. Cancer Research, 69(18), 7151-7156.
19. Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., and Bray, F. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians, 71(3), 209-249.
20. Troisi, R., Bjørge, T., Gissler, M., Grotmol, T., Kitahara, C. M., Myrtveit Saether, S. M., ... and Glimelius, I. (2018). The role of pregnancy, perinatal factors and hormones in maternal cancer risk: a review of the evidence. Journal of Internal Medicine, 283(5), 430-445.
21. Wardle, J., Robb, K., Vernon, S., and Waller, J. (2015). Screening for prevention and early diagnosis of cancer. American psychologist, 70(2), 119.
22. World Health Organization. (2010). A conceptual framework for action on the social determinants of health.
23. World Health Organization. (2021). Global monitoring report on financial protection in health 2021. World Health Organization.
24. World Health Organization. (2022). Regional strategic framework for vaccine-preventable diseases and immunization in the Western Pacific 2021-2030.
25. World Health Organization. (2023). Global breast cancer initiative implementation framework: assessing, strengthening and scaling-up of services for the early detection and management of breast cancer. World Health Organization.
26. World Health Organization. (2023). Tobacco and chronic obstructive pulmonary disease (COPD): WHO tobacco knowledge summaries. World Health Organization.

27.World Health Organization. (2024). WHO global survey on the inclusion of cancer care in health-benefit packages, 2020–2021. World Health Organization.