Authors : Bairmani M. S.

Volume/Issue : Volume 10 - 2025, Issue 4 - April

Google Scholar : https://tinyurl.com/3z8z299j

Scribd : https://tinyurl.com/y6awtadz

DOI : https://doi.org/10.38124/ijisrt/25apr906

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Abstract : Silver nanoparticles (Ag NPs) among the nanomaterials have appeared numerous improved properties, that empowered analysts in different areas of science to create unused made items. Ag NPs is recognized with its biocompatibility , easy to synthesis and appeared modern physicochemical properties, adjacent to the distinguished antibacterial action towards microorganisms. In this research we Ag NPs have been synthesized using Sodiumborohydrate as a reduction agent (Borohydrate method) or strategy. The outcome nanoparticals was characterized with Uv-Vis which appears peck absorbance at 410 nm which acclimate the changed color of silver nitrate to golden yellow color of silver nanoparticles and by SEM which reveled 50 nm approx. in a circular shape. E-coli as gram-ve pathogenic microscopic organisms have been utilized to assess the cytotoxic efficiency of Ag NPs using hole diffusion strategy. distinct zones of inhibition around the hole, suggesting that the silver nanoparticles effectively inhibit the growth of E.coli. This result has significance to address with the increasing problem of antibiotic resistance.

Keywords : Borohydrate Method, Silver Nanoparticles, MDR, Pathogenic E. coli.

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