Authors : Dr. R. K. Sangeetha; S. Shimna; K. Hifathulla; A. Rohith Kannan

Volume/Issue : Volume 11 - 2026, Issue 10 - October

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Google Scholar : https://tinyurl.com/e6e93jhp

DOI : https://doi.org/10.38124/ijisrt/26Oct1016

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

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Abstract : A simple, rapid and sensitive ultra-fast liquid chromatographic technique was developed for the determination of heavy metals in pharmaceutical dosage form. Lead and copper were detected and quantified at µg level in simvastatin, a pharmaceutical product used in the treatment of lowering cholesterol level in body. Calcium disodium edetate was used as the chelating agent.

Keywords : UFLC-PDA, Method Validation, Simvastatin, Lead Nitrate, Copper Sulphate, ICH Guidelines.

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