Authors :
Ashok Agarwal
Volume/Issue :
Volume 11 - 2026, Issue 8 - August
Google Scholar :
https://tinyurl.com/y3mzwnjz
Scribd :
https://tinyurl.com/2mspa6cc
DOI :
https://doi.org/10.38124/ijisrt/26aug406
Note : A published paper may take 4-5
working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and
ResearchGate.
Abstract :
The chemical process industry is indispensable to modern society but involves inherent risks associated with toxic,
flammable, reactive and corrosive substances, high pressures and temperatures, complex process interactions and large
inventories. Although major accidents are relatively infrequent, their consequences may extend beyond the plant boundary
and affect workers, emergency responders, communities, infrastructure and the environment. This review re-examines
chemical-industry safety and security from an integrated process-safety and disaster-risk-management perspective, using
the author's earlier article as its foundation while substantially rewriting and expanding its content. The review covers
hazard identification, HAZOP, What-If analysis, FMEA, fault-tree analysis, Layer of Protection Analysis, quantitative risk
assessment, inherently safer design, management of change, safety instrumented systems, mechanical integrity, human
factors, emergency planning and community preparedness. It also considers natural-hazard-triggered technological
accidents, the Indian regulatory framework and international approaches including OSHA Process Safety Management and
ISO 45001. Recent developments in digitalization, sensors, predictive analytics, digital twins and artificial intelligence are
examined as opportunities for early warning and decision support, together with their cybersecurity and human-factor
implications. The review concludes that effective chemical safety cannot depend on a single safeguard. It requires a
continuously verified system integrating safer design, reliable equipment, competent people, strong safety culture,
emergency preparedness, physical and cyber security, and organizational learning.
Keywords :
Chemical Process Safety; Disaster Risk Management; HAZOP; LOPA; Inherently Safer Design; Emergency Preparedness; Process Safety Management; Chemical Security.
References :
- American Institute of Chemical Engineers, Center for Chemical Process Safety. (2007). Guidelines for Risk Based Process Safety. AIChE/CCPS.
- American Institute of Chemical Engineers, Center for Chemical Process Safety. (2011). Process Safety Leading and Lagging Metrics. AIChE/CCPS.
- International Electrotechnical Commission. (2016). IEC 61511-1:2016 Functional Safety—Safety Instrumented Systems for the Process Industry Sector—Part 1. IEC.
- International Labour Organization. (1993). Prevention of Major Industrial Accidents. ILO.
- International Labour Organization. (2014). Safety and Health in the Use of Chemicals at Work. ILO.
- International Organization for Standardization. (2018). ISO 45001:2018 Occupational Health and Safety Management Systems—Requirements with Guidance for Use. ISO.
- Ministry of Environment and Forests, Government of India. (1996). Chemical Accidents (Emergency Planning, Preparedness and Response) Rules, 1996.
- National Disaster Management Authority, Government of India. (2007). National Disaster Management Guidelines: Chemical Disasters. NDMA.
- Occupational Safety and Health Administration. (1992). Process Safety Management of Highly Hazardous Chemicals, 29 CFR 1910.119. U.S. Department of Labor.
- Occupational Safety and Health Administration. (2026). Process Safety Management: Overview. U.S. Department of Labor.
- United Nations Environment Programme. (2006). Strategic Approach to International Chemicals Management (SAICM). UNEP.
- United Nations Environment Programme. (2019). Global Chemicals Outlook II: From Legacies to Innovative Solutions. UNEP.
- United Nations Environment Programme. (2024). Global Framework on Chemicals—For a Planet Free of Harm from Chemicals and Waste. UNEP.
- United Nations Economic Commission for Europe. (2018). Safety Guidelines and Good Practices for Hazardous Activities. UNECE.
- Kletz, T. A. (1999). HAZOP and HAZAN: Identifying and Assessing Process Industry Hazards (4th ed.). Institution of Chemical Engineers.
- Kletz, T. A., & Amyotte, P. (2010). Process Plants: A Handbook for Inherently Safer Design (2nd ed.). CRC Press.
- Mannan, S. (Ed.). (2012). Lees’ Loss Prevention in the Process Industries (4th ed.). Butterworth-Heinemann.
- Rausand, M. (2014). Risk Assessment: Theory, Methods, and Applications. Wiley.
- Reason, J. (1997). Managing the Risks of Organizational Accidents. Ashgate.
- Sklet, S. (2006). Safety barriers: Definition, classification, and performance. Journal of Loss Prevention in the Process Industries, 19(5), 494–506.
- Government of India. (1986). Environment (Protection) Act, 1986.
- Government of India. (1989). Manufacture, Storage and Import of Hazardous Chemical Rules, 1989.
- Government of India. (2005). Disaster Management Act, 2005.
- European Parliament and Council of the European Union. (2012). Directive 2012/18/EU on the control of major-accident hazards involving dangerous substances (Seveso III).
- European Commission. (2012). Guidance on the preparation of a safety report for establishments covered by the Seveso III Directive.
- National Institute for Occupational Safety and Health. (2015). Hierarchy of Controls. Centers for Disease Control and Prevention.
- International Organization for Standardization. (2015). ISO 14001:2015 Environmental Management Systems—Requirements with Guidance for Use. ISO.
- International Journal of Innovative Science and Research Technology. (2026). Author Guidelines and Manuscript Requirements. IJISRT.
The chemical process industry is indispensable to modern society but involves inherent risks associated with toxic,
flammable, reactive and corrosive substances, high pressures and temperatures, complex process interactions and large
inventories. Although major accidents are relatively infrequent, their consequences may extend beyond the plant boundary
and affect workers, emergency responders, communities, infrastructure and the environment. This review re-examines
chemical-industry safety and security from an integrated process-safety and disaster-risk-management perspective, using
the author's earlier article as its foundation while substantially rewriting and expanding its content. The review covers
hazard identification, HAZOP, What-If analysis, FMEA, fault-tree analysis, Layer of Protection Analysis, quantitative risk
assessment, inherently safer design, management of change, safety instrumented systems, mechanical integrity, human
factors, emergency planning and community preparedness. It also considers natural-hazard-triggered technological
accidents, the Indian regulatory framework and international approaches including OSHA Process Safety Management and
ISO 45001. Recent developments in digitalization, sensors, predictive analytics, digital twins and artificial intelligence are
examined as opportunities for early warning and decision support, together with their cybersecurity and human-factor
implications. The review concludes that effective chemical safety cannot depend on a single safeguard. It requires a
continuously verified system integrating safer design, reliable equipment, competent people, strong safety culture,
emergency preparedness, physical and cyber security, and organizational learning.
Keywords :
Chemical Process Safety; Disaster Risk Management; HAZOP; LOPA; Inherently Safer Design; Emergency Preparedness; Process Safety Management; Chemical Security.