Authors : Jyoti Sharma

Volume/Issue : Volume 9 - 2024, Issue 1 - January

Google Scholar : http://tinyurl.com/3jyj9jud

Scribd : http://tinyurl.com/9mx9fk3w

DOI : https://doi.org/10.5281/zenodo.10629148

Abstract : Aim of this research is to define the role of chemicals in pharmaceutical research There are several steps in pharmaceutical research. Some of them are choosing of raw material, formation of API and addition of excipient. In all these steps chemicals play essential role. Chemicals use in formation of API and also several chemicals are using as excipients to support medicine and provide stability. A large no. of chemicals are use as solvents, reagents and as catalysts also. Thus knowledge of chemicals and their availability is major condition in preparation of any medicine. Chemicals make pharmaceutical research easier and faster. In this article we will see some examples of chemicals form as API(paracetamol, Oxymetazoline hydrochloride etc), some example of chemicals use as anti-adherents(for example Talc and microcrystalline cellulose), lubricants(talc, glidants etc), fillers (lactose, sucrose etc)and preservatives etc. They are said to be excipients. Here we will see some examples of chemicals which use as catalyst, reagents and solvents. An important step of pharma research is analysis which is depend on analytical techniques like spectroscopy(UV-vis, IR, MASS etc.) and chromatography(GS , HPLC, HPAC etc.). Analysis techniques are carry out for various purpose like to identify raw materials, to purify drug and to remove all side affects which leads to the formation of very useful and desired medicine. Several chemicals are their which use in these analysis techniques. Thus in every step chemicals come out essential factor in pharmaceutical research. Role of chemicals are very vast.

Keywords : Essential, Chemicals, Analysis, APIs, Excipients.