Authors :
Kanchan. Y. Gomkar; Rakesh Y. Bhute
Volume/Issue :
Volume 11 - 2026, Issue 3 - March
Google Scholar :
https://tinyurl.com/f5mtsw9x
Scribd :
https://tinyurl.com/y7n587e4
DOI :
https://doi.org/10.38124/ijisrt/26mar1116
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
In conclusion, the developed herbal foot crack cream formulated with Hibiscus, Fenugreek, and Licorice extracts shows
significant potential as a natural and effective treatment for heel fissures. The combination of these medicinal plants provides a
synergistic effect, offering multiple therapeutic benefits such as hydration, anti-inflammatory action, antimicrobial protection,
antioxidant activity, and enhanced wound healing. These properties collectively help in softening dry and hardened skin, reducing pain
and inflammation, and promoting faster repair of cracked heels. The use of an oil-in-water cream base further ensures proper absorption,
stability, and ease of application, making the formulation suitable for regular use. Compared to conventional synthetic products, this
herbal formulation is safer, cost-effective, and less likely to cause adverse reactions, thereby improving patient compliance and comfort.
Overall, the study highlights the importance of integrating traditional herbal knowledge with modern pharmaceutical techniques to develop
effective skincare solutions. The formulated cream can serve as a promising alternative in the management of heel fissures and related skin
conditions. However, further clinical evaluation and long-term studies are recommended to confirm its efficacy, safety, and
broader dermatologicalapplications.
References :
- M. Shoeb, V. Daldale, N. S. Pathan, and V. Hingane, ―A Research on Formulation and Evaluation of Herbal Foot Cream,‖ 2023. [Online]. Available: www.ijaresm.com
- Biologically Active Compounds from the Genus Hibiscus. Academia.edu. 2021.
- Hibiscus Rosa-Sinensis - an overview. ScienceDirect Topics.
- Fenugreek - Drugs and Lactation Database. NCBI Bookshelf. 2025.
- Lim TK. Edible Medicinal and Non-Medicinal Plants. Volume 3. Netherlands: Springer; 2012.
- Kirtikar KR, Basu BD. Indian Medicinal Plants. 2nd ed. Dehradun: International Book Distributors; 2001.
- Shahid M, Dutta U. Morphological and pharmacognostic evaluation of Hibiscus rosa- sinensis flowers. J Pharmacogn Phytochem. 2018;7(3):2015–20.
- Lim TK. Edible Medicinal and Non-Medicinal Plants. Springer; 2012.
- LMohanty S, et al. Phytochemical evaluation of Hibiscus rosa-sinensis flower extract. Int J Pharm Sci Rev Res. 2015;32(2):122–7.
- Prasad NK, et al. Phenolic content and antioxidant capacity of hibiscus extract. Food Chem. 2009;115(1):44–50.
- Kumar S, et al. Evaluation of wound healing activity of Hibiscus rosa-sinensis flowers. J Ethnopharmacol. 2008;120(1):1–7.
- Singh R, et al. Antimicrobial activity of Hibiscus rosa-sinensis extracts. Pharm Biol. 2002;40(4):253–6.
- Nadkarni KM. Indian Materia Medica. Vol. 1. Mumbai: Popular Prakashan; 2009.
- Shahid M, Dutta U. J Pharmacogn Phytochem. 2018;7(3):2015–20.
- Mohanty S, et al. Int J Pharm Sci Rev Res. 2015;32(2):122–7.
- Bown D. Encyclopedia of Herbs and Their Uses. London: Dorling Kindersley; 2001.
- Nadkarni KM. Indian Materia Medica. Vol. 1. Mumbai: Popular Prakashan; 2009.
- Acharya SN, Srichamroen A, Basu S. Improvement in functional properties of Fenugreek. Food Chem. 2006;98(3):451–7.
- Petropoulos GA. Fenugreek — The genus Trigonella. London: Taylor & Francis; 2002.
- Srinivasan K. Fenugreek: Pharmacology and phytochemistry. Food Rev Int. 2006;22(2):20324.
- Dixit P, Ghaskadbi S, Mohan H, Devasagayam TPA. Antioxidant properties of Fenugreek seeds. Food Chem. 2005;93(2):2539.
- Thirunavukkarasu P, et al. Wound healing activity of Trigonella foenum-graecum seed extract. Asian J Pharm Clin Res. 2012;5(4):74–8.
- Meghwal M, Goswami TK. Anti-inflammatory and antimicrobial potential of Fenugreek extracts. J Food Sci Technol. 2012;49(2):255–9.
- Pandey M, et al. Traditional uses of Fenugreek in skin ailments. J Ethno10. Srinivasan K. Food R
- Evans WC. Trease and Evans’ Pharmacognosy. 16th ed. London: Saunders/Elsevier; 2009.
- Sharma PC, Yelne MB, Dennis TJ. Database on Medicinal Plants Used in Ayurveda. Vol. 3. New Delhi: CCRAS; 2005.
- Kirtikar KR, Basu BD. Indian Medicinal Plants. Vol. 3. Dehradun: Bishen Singh Mahendra Pal Singh; 1991.
- Fiore C, Eisenhut M, Krausse R, Ragazzi E, Pellati D, Armanini D. Antiviral and antimicrobial properties of Licorice constituents. Mini Rev Med Chem. 2008;8(9):912– 20.
- Pastorino G, Cornara L, Soares S, Rodrigues F, Oliveira M. Licorice phytochemistry and pharmacology. Phytother Res. 2018;32(12):2323–39.
- Armanini D, Fiore C. Anti-inflammatory effects of glycyrrhizin. J Endocrinol Invest. 2002;25(7):618–23.
- Lee SY, Kim JH, Jung G. Antimicrobial effect of Glycyrrhiza glabra extracts. J Ethnopharmacol. 2013;148(2):515–23.
- Yokota T, Nishio H, Kubota Y, Mizoguchi M. The skin-lightening effects of glabridin. Phytother Res. 1998;12(2):S65–S68.
- Nadkarni KM. Indian Materia Medica. Vol. 1. Mumbai: Popular Prakashan; 2009.
- World Health Organization. WHO Monographs on Selected Medicinal Plants. Vol. 2. Geneva: WHO; 2004.
- Kokate CK, Purohit AP, Gokhale SB. Pharmacognosy. 56th ed. Pune: Nirali Prakashan; 2022.
- WHO. Quality Control Methods for Medicinal Plant Materials. Geneva: World Health Organization; 1998. Kirtikar KR, Basu BD. Indian Medicinal Plants. 2nd ed. Dehradun: Bishen Singh Mahendra Pal Singh; 1991.
- Evans WC. Trease and Evans Pharmacognosy. 16th ed. London: Saunders/Elsevier; 2009.
- Rowe RC, Sheskey PJ, Quinn ME. Handbook of Pharmaceutical Excipients. 7th ed. London: Pharmaceutical Press; 2012
In conclusion, the developed herbal foot crack cream formulated with Hibiscus, Fenugreek, and Licorice extracts shows
significant potential as a natural and effective treatment for heel fissures. The combination of these medicinal plants provides a
synergistic effect, offering multiple therapeutic benefits such as hydration, anti-inflammatory action, antimicrobial protection,
antioxidant activity, and enhanced wound healing. These properties collectively help in softening dry and hardened skin, reducing pain
and inflammation, and promoting faster repair of cracked heels. The use of an oil-in-water cream base further ensures proper absorption,
stability, and ease of application, making the formulation suitable for regular use. Compared to conventional synthetic products, this
herbal formulation is safer, cost-effective, and less likely to cause adverse reactions, thereby improving patient compliance and comfort.
Overall, the study highlights the importance of integrating traditional herbal knowledge with modern pharmaceutical techniques to develop
effective skincare solutions. The formulated cream can serve as a promising alternative in the management of heel fissures and related skin
conditions. However, further clinical evaluation and long-term studies are recommended to confirm its efficacy, safety, and
broader dermatologicalapplications.