Response to Treatment in Osteoarthritis Clinical Trial: A Narrative Review


Authors : Dr. Srushti Suryawanshi; Dr. Swati Shinde

Volume/Issue : Volume 8 - 2023, Issue 12 - December

Google Scholar : http://tinyurl.com/3erwezay

Scribd : http://tinyurl.com/44mkymjd

DOI : https://doi.org/10.5281/zenodo.10454192

Abstract : Background- The prevalence of knee osteoarthritis is high Comparing Indians to Western individuals, and the prevalence of frequent squatting in daily routines, particularly among women. In osteoarthritis, Pathological alterations have occurred in all joint structures. Individuals who do not exhibit favourable responses to traditional medical treatments and are either unwilling undergo surgical procedures have a specific requirement for such medications. The objective of this study was to investigate whether homoeopathic medicines can effectively address the management of knee joint pain in individuals with Osteoarthritis.  Method- The eligibility criteria are as follows: Papers were evaluated and chosen based on the homoeopathic medicine used in this study using PICO Criteria., which met the following criteria:-  Year 2000- 2022  Sample size, Age group, Male And Female Ratio.  Method Use For Study  Outcome Measure  Published in English  Homeopathic medicine is used. Information Source-Relevant literature or research articles were taken from various databases such as PubMed, Google Scholar, Scopus, Hombrex, and Research Gate.  Result- A comprehensive review identified a Total of 33 Experimental and Controlled clinical trials for screening. Thorough screening, the number of eligible papers was determined to be 23. Some articles lacked information on age groups, and there were discrepancies in properly specifying the male-to-female ratio. Additionally, certain studies did not incorporate any outcome measures.  Conclusion- In this study, we clearly understand that homeopathic therapeutic medicine work well on Osteoarthritis. Rhus Toxicodendron medicine is used in 9 articles. Then Calcarea Flour 5, Calcarea carb 4, and Bryonia Alba 4 in Article were used. Individualized homeopathic medicine was ineffective due to a lack of trial reports. The most commonly used scales are the WOMAC Scale, VAS Scale, and KOOS Score pain measuring movement, duration of rest, stiffness, and incidence of OA. For Radiological assessment Kellgren and Lawrence systems of classification of knee osteoarthritis severity 5 grade classification and X ray knee used.

Keywords : Osteoarthritis, ‘Osteoarthrosis’, ‘Gonarthrotic’, ‘Homeopathy’, ‘Alternative Medicine’, ‘Complementary Medicine’, ‘Effective Measure’.

Background- The prevalence of knee osteoarthritis is high Comparing Indians to Western individuals, and the prevalence of frequent squatting in daily routines, particularly among women. In osteoarthritis, Pathological alterations have occurred in all joint structures. Individuals who do not exhibit favourable responses to traditional medical treatments and are either unwilling undergo surgical procedures have a specific requirement for such medications. The objective of this study was to investigate whether homoeopathic medicines can effectively address the management of knee joint pain in individuals with Osteoarthritis.  Method- The eligibility criteria are as follows: Papers were evaluated and chosen based on the homoeopathic medicine used in this study using PICO Criteria., which met the following criteria:-  Year 2000- 2022  Sample size, Age group, Male And Female Ratio.  Method Use For Study  Outcome Measure  Published in English  Homeopathic medicine is used. Information Source-Relevant literature or research articles were taken from various databases such as PubMed, Google Scholar, Scopus, Hombrex, and Research Gate.  Result- A comprehensive review identified a Total of 33 Experimental and Controlled clinical trials for screening. Thorough screening, the number of eligible papers was determined to be 23. Some articles lacked information on age groups, and there were discrepancies in properly specifying the male-to-female ratio. Additionally, certain studies did not incorporate any outcome measures.  Conclusion- In this study, we clearly understand that homeopathic therapeutic medicine work well on Osteoarthritis. Rhus Toxicodendron medicine is used in 9 articles. Then Calcarea Flour 5, Calcarea carb 4, and Bryonia Alba 4 in Article were used. Individualized homeopathic medicine was ineffective due to a lack of trial reports. The most commonly used scales are the WOMAC Scale, VAS Scale, and KOOS Score pain measuring movement, duration of rest, stiffness, and incidence of OA. For Radiological assessment Kellgren and Lawrence systems of classification of knee osteoarthritis severity 5 grade classification and X ray knee used.

Keywords : Osteoarthritis, ‘Osteoarthrosis’, ‘Gonarthrotic’, ‘Homeopathy’, ‘Alternative Medicine’, ‘Complementary Medicine’, ‘Effective Measure’.

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