The tissue perfusion marker (lactate,
ScVO2) has limitations. Therefore, the PvaCO2 gap is
described as a parameter reflecting tissue hypoperfusion.
Since occult regional ischemia, ie undetected at the
systemic level, is considered a major contributor to
morbidity and mortality after major trauma and in
other critically ill patients, early detection of regional
hypoxia is necessary. Traditionally, oxygenation is
measured with invasive devices. NIRS is further used as
a noninvasive monitoring technique that assesses
regional brain oxygen saturation.
PvaCO2 gap, NIRS, StO2, Sepsis.