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Rapid Assessment of Therapeutic Potential and Antimicrobial Properties of Mimosa pudica on Pseudomonas aeruginosa from Clinical Samples Obtained at Alex Ekwueme Federal University Ndufu Alike Ikwo Clinic, Ebonyi State Nigeria


Authors : Owolabi, O. J.; Amechi-Nnaji, V. O.; Kelechi- Mathew, O. O.; Akindele, K. I.; Adeshina, A. A.; Oyewunmi, A. A.

Volume/Issue : Volume 11 - 2026, Issue 5 - May


Google Scholar : https://tinyurl.com/5yxz9ytv

Scribd : https://tinyurl.com/k964bter

DOI : https://doi.org/10.38124/ijisrt/26May1550

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : susceptible to Gentamicin and Ciprofloxacin, while Ceftriaxone showed 80% susceptibility. Antimicrobial susceptibility testing of Mimosa pudica extracts demonstrated notable inhibitory activity against the isolates. Both ethanolic and aqueous extracts, prepared at concentrations of 100, 50, and 25 mg/ml, showed concentration-dependent inhibition zones. The ethanolic extract produced inhibition zones between 9 –13 mm, while aqueous extracts ranged between 10 –13 mm at 100 mg/ml. Although Gentamicin (positive control) showed higher inhibition (15 –26 mm), the results confirm that M. pudica had inhibitory effects on Pseudomonas species tested. The results affirmed that Mimosa pudica possesses therapeutic properties and proved to be a promising source of natural antimicrobial agents, especially against multidrug-resistant pathogens like Pseudomonas aeruginosa. This supports its potential use in developing alternative therapies to combat antibiotic resistance.

Keywords : Mimosa pudica, Pseudomonas aeruginosa, Antimicrobial Susceptibility, Inhibitory Effects.

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susceptible to Gentamicin and Ciprofloxacin, while Ceftriaxone showed 80% susceptibility. Antimicrobial susceptibility testing of Mimosa pudica extracts demonstrated notable inhibitory activity against the isolates. Both ethanolic and aqueous extracts, prepared at concentrations of 100, 50, and 25 mg/ml, showed concentration-dependent inhibition zones. The ethanolic extract produced inhibition zones between 9 –13 mm, while aqueous extracts ranged between 10 –13 mm at 100 mg/ml. Although Gentamicin (positive control) showed higher inhibition (15 –26 mm), the results confirm that M. pudica had inhibitory effects on Pseudomonas species tested. The results affirmed that Mimosa pudica possesses therapeutic properties and proved to be a promising source of natural antimicrobial agents, especially against multidrug-resistant pathogens like Pseudomonas aeruginosa. This supports its potential use in developing alternative therapies to combat antibiotic resistance.

Keywords : Mimosa pudica, Pseudomonas aeruginosa, Antimicrobial Susceptibility, Inhibitory Effects.

Paper Submission Last Date
30 - June - 2026

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