The lower respiratory tract infections are
a prime cause of morbidity and mortality in our country.
A hospital based cross sectional study was fulfilled with
an objective to study the bacterial pathogens isolated
and susceptibility pattern from patients of lower
respiratory tract infections.
Methods: Overall 826 lower respiratory specimens such
as sputum, endotracheal aspirates, bronchial aspirate
and pleural fluid were cultured aerobically using
standard microbiological technique as per Clinical
Laboratory Standard Institute guidelines.
Results: Out of 826 lower respiratory specimens,
523(63.3%) bacterial pathogens were recovered.
Streptococcus pyogenes (65.8%) was the commonest
isolate and increase isolation rate was observed in the
male 291(55.64%) of 60-79 years age groups. Most of the
pathogens showed sensitive to macrolides and
aminoglycoisides, however, Streptococcus pyogenes and
Staphylococcus aureus were most susceptible to
tetracycline 262(75.9%) and azithromycin 53(73.6%). In
case of Pseudomonas aeruginosa were sensitive to
amikacin 22(64.7%) while Acinetobactor baumani were
found sensitive to amikacin 16(80%) and Klebsiella
pneumoniae was sensitive to penicillin 37(71.1%).
Conclusions: For effective treatment of typical bacterial
lower respiratory tract infections, bacterial culture and
antibiotic sensitivity testing are required.
Keywords : Lower Respiratory Tract Infections, Bacterial Pathogens, Antibiotic sensitivity