This review focuses the prevalence of Tuberculosis in patients of diabetes. Tuberculosis & Diabetes are very joint infections & both are showing an increasing trend. Tuberculosis is a infection and the pathogen responsible for this is Mycobacterium tuberculosis. The Mycobacterium is the bacteria primarily responsible for lung infection and this infection some times might be spread in other organ system beyond the lungs. Diabetes mellitus is a category of a typical metabolic disorder responsible for increased blood sugar level in a person . In diabetes the body is not having ability to produce sufficient insulin or the cells of the body do not respond in a proper way to the insulin that is produced inside body. Most of the time patients of diabetes are very much susceptible against different types of infections & tuberculosis is one of most important amongst them. Prevalence of tuberculosis is three to five times more in patients of diabetes than the non-diabetic people. There is more difficulty in the management of patients of tuberculosis who are having diabetes due to postponement in diagnosis as these both the disease have some common symptoms such as lethargy, weight loss & anorexia etc. The risk of diabetes in patients of tuberculosis should be considered because patient have very poor clinical response to Anti tubercular drugs (ATT) & correspondingly the doubt of accompanying tuberculosis infection should be measured in patient with uncontrolled diabetes. Recent different systematic reviews showed that diabetes is connected with a bigger risk of Tuberculosis. The main aim of the present review is to appraise the epidemiology of diabetes mellitus and tuberculosis , the effect of diabetes on tuberculosis and vice versa and to explore the critical and urgent need of the good-quality experimental application of research which may be responsible for creating vigorous action plans to address this double burden.

Keywords : Tuberculosis; Mycobacterium tuberculosis Diabetes, Insulin; Glucose intolerance; Blood sugar level clinical implementation research.