Cancer is one of the most important health problems in the world. In developed countries, about 55 % of the burden of diseases is associated with cancer. The incidence of cancer is rapidly increasing in these countries. Breast cancer is the most common cancer in females in Iraq and the world continues to be one of the main causes of cancer-related death. The prevalence of breast cancer in females is rising. The mortality rate by breast cancer can be reduce by regular breast cancer screening program for early detection and prevention. Methodology: - A descriptive study was performed to the determine prevalence and Mortality among women with Breast Cancer. The study was carried out in Al Sadr medical city and Middle Euphrates Cancer Center on Al Najaf Al -Ashraf city during the period from January 11th, 2019 to July 12th 2019. A Non Probability "purposive" sample of (413) patients with breast cancer were selected based on criteria of female only in sample study and 2017 and 2018 years only. Result: - Data were collected by patient's records to identify the prevalence and mortality. The Data was analysis through using mean, Standard Deviation, frequency, and percentage. The study findings that the highest age group of sample was ranging from (46 – 60) have 47.1%. Majority prevalence the patients related to side of breast cancer its right side, most of the prevalence and mortality of breast cancer on 2017 more than 2018. Conclusion: - The study concluded that: according to our age group (46-60) years who admitted to hospitals, Majority of the study sample showed urban residential, married, illiterate and housewife. Demonstrated the most women who are admitted to hospitals are overweight. Majority prevalence the patients related to side of breast cancer its right side. Recommendations: - Increased health awareness and early treatment have led to a reduction in prevalence and mortality, so we recommend focusing on raising community health awareness for prevention and early detection of disease, raising the level of preventive awareness of the community to avoid risk factors such as obesity. The development of health programs for early detection and prevention of the spread of breast cancer, especially in the urbans, extensive study on the prevalence and mortality of breast cancer throughout the country

Keywords : Prevalence, Mortality, Women, Breast Cancer, Al-Najaf Al-Ashraf City.