Authors :
Ghismel NZAMBA MOUSSAVOU; Paulin NKOLO; Joefred MBOGHO ABOGO; Elvis OTOGO N’NANG; Cédric SIMA OBIANG; Jacques LEBIBI; Jean-Bernard BONGUI
Volume/Issue :
Volume 8 - 2023, Issue 6 - June
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/k8hhx8c7
DOI :
https://doi.org/10.5281/zenodo.8124191
Abstract :
Artemisia afra and Artemisia annua are two
medicinal plants used in the treatment of several diseases
including malaria in South Africa and China respectively.
In Gabon, these plant species are cultivated by the
Maison de l'Artemisia, which promotes them in the fight
against malaria. The objective of this work was to carry
out a phytochemical screening and to evaluate the anti-
radical and antibacterial properties of extracts of A. afra
and A. annua cultivated in Gabon. Phytochemical
constituents were identified using the tube reaction
method. Bacterial susceptibility was determined using the
diffusion method while scavenging activity was assessed
by the DPPH free radical test. Phytochemical analysis
showed that both plant extracts were rich in polyphenols
and terpene compounds and possessed good anti-radical
activity based on DPPH free radical scavenging. The
aqueous extract of A. afra exhibited the strongest anti-
radical activity with an IC50 of 0.02 mg/ml and an AAI of
2.4. The antibacterial activity shows that the ethanolic
extract of A. afra inhibits the growth of E. coli while the
ethanolic extract of A. annua inhibits the growth of S.
aureus and S. dysenteriae. Our study shows that A. afra
and A. annua plants grown in Gabon contain various
families of chemical compounds and possess anti-radical
and antibacterial activities. It also shows that A. afra has
an anti-radical property superior to that of A. annua.
Keywords :
Artemisia afra, Artemisia annua, Phytochemical Study, Anti-Radical Activity, Antibacterial Activity.
Artemisia afra and Artemisia annua are two
medicinal plants used in the treatment of several diseases
including malaria in South Africa and China respectively.
In Gabon, these plant species are cultivated by the
Maison de l'Artemisia, which promotes them in the fight
against malaria. The objective of this work was to carry
out a phytochemical screening and to evaluate the anti-
radical and antibacterial properties of extracts of A. afra
and A. annua cultivated in Gabon. Phytochemical
constituents were identified using the tube reaction
method. Bacterial susceptibility was determined using the
diffusion method while scavenging activity was assessed
by the DPPH free radical test. Phytochemical analysis
showed that both plant extracts were rich in polyphenols
and terpene compounds and possessed good anti-radical
activity based on DPPH free radical scavenging. The
aqueous extract of A. afra exhibited the strongest anti-
radical activity with an IC50 of 0.02 mg/ml and an AAI of
2.4. The antibacterial activity shows that the ethanolic
extract of A. afra inhibits the growth of E. coli while the
ethanolic extract of A. annua inhibits the growth of S.
aureus and S. dysenteriae. Our study shows that A. afra
and A. annua plants grown in Gabon contain various
families of chemical compounds and possess anti-radical
and antibacterial activities. It also shows that A. afra has
an anti-radical property superior to that of A. annua.
Keywords :
Artemisia afra, Artemisia annua, Phytochemical Study, Anti-Radical Activity, Antibacterial Activity.
