Authors :
Bourdettes Meye; Dieudonné Nkoghe; Robert Eya'ama Mve; Joseph Privat Ondo; Cédric Sima Obiang; Louis-Clément Obame Engonga
Volume/Issue :
Volume 8 - 2023, Issue 7 - July
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/mu64uxaz
DOI :
https://doi.org/10.5281/zenodo.8265061
Abstract :
Background: The end of 2019 was marked by the
emergence of a new virus called SARS-CoV-2 responsible
for COVID-19 (Corona Virus Disease - 2019). This viral
disease, which took off in the People's Republic of China,
rapidly mutated into a pandemic by March 2020. The
therapeutic management of this new disease has been the
subject of much speculation, given the absence of a
vaccine. The high cure rate observed on Gabonese soil
prompted the launch of this study.
The objective of this study was to conduct a single-center
retrospective observational study to assess the time to
cure in symptomatic COVID-19 patients hospitalized at
Amissa Bongo Regional Hospital Center of Franceville
(CHRAB). Method: Between May 16 and August 31,
2020, the medical records of all patients suffering from
Covid-19 and treated by the "national COVID-19
protocol" were collected. Viral diagnosis was performed
by gene amplification on the Applied Biosystems AB 7500
Real Time PCR System, according to the SARS-CoV-2
diagnostic protocol validated by the Africa CDC and the
African Union.
Results: The speed of recovery was related to the presence
or absence of comorbidity in treated patients. Liver
damage marked by elevated serum transaminases was
observed in these patients, due to heavy consumption of
often-hepatotoxic drugs, while renal function was
generally unaffected. Anemia is recurrent in these
patients, and consequently increases their plasma
bilirubin levels. Conclusion: This study shows that the 45
to 50 age group is the one most affected by the SARS CoV-
2 virus, and that women are 1.2 times more contaminated
than men. Of all the reasons for consultation recorded,
fever is the first symptom, followed by cough and
dyspnea. The "Hydroxychloroquine-Azithromycin"
combination is a therapeutic protocol adopted by many
countries around the world. Its efficacy depends on the
absence of comorbidity in treated patients. Most patients
recover after 10 days of treatment.
Keywords :
National Therapeutic Protocol, SARS-CoV-2, COVID-19, Amissa Bongo Regional Hospital Center.
Background: The end of 2019 was marked by the
emergence of a new virus called SARS-CoV-2 responsible
for COVID-19 (Corona Virus Disease - 2019). This viral
disease, which took off in the People's Republic of China,
rapidly mutated into a pandemic by March 2020. The
therapeutic management of this new disease has been the
subject of much speculation, given the absence of a
vaccine. The high cure rate observed on Gabonese soil
prompted the launch of this study.
The objective of this study was to conduct a single-center
retrospective observational study to assess the time to
cure in symptomatic COVID-19 patients hospitalized at
Amissa Bongo Regional Hospital Center of Franceville
(CHRAB). Method: Between May 16 and August 31,
2020, the medical records of all patients suffering from
Covid-19 and treated by the "national COVID-19
protocol" were collected. Viral diagnosis was performed
by gene amplification on the Applied Biosystems AB 7500
Real Time PCR System, according to the SARS-CoV-2
diagnostic protocol validated by the Africa CDC and the
African Union.
Results: The speed of recovery was related to the presence
or absence of comorbidity in treated patients. Liver
damage marked by elevated serum transaminases was
observed in these patients, due to heavy consumption of
often-hepatotoxic drugs, while renal function was
generally unaffected. Anemia is recurrent in these
patients, and consequently increases their plasma
bilirubin levels. Conclusion: This study shows that the 45
to 50 age group is the one most affected by the SARS CoV-
2 virus, and that women are 1.2 times more contaminated
than men. Of all the reasons for consultation recorded,
fever is the first symptom, followed by cough and
dyspnea. The "Hydroxychloroquine-Azithromycin"
combination is a therapeutic protocol adopted by many
countries around the world. Its efficacy depends on the
absence of comorbidity in treated patients. Most patients
recover after 10 days of treatment.
Keywords :
National Therapeutic Protocol, SARS-CoV-2, COVID-19, Amissa Bongo Regional Hospital Center.
