Authors :
Dr. Rajesh Kumar Thakur; Dr. Prerna Kataria; Dr. Nitigya Kumar
Volume/Issue :
Volume 10 - 2025, Issue 6 - June
Google Scholar :
https://tinyurl.com/mryup59d
DOI :
https://doi.org/10.38124/ijisrt/25jun819
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Periodontal disease is a chronic, multifactorial condition that affects a significant portion of the global population.
Traditional approaches to its management have often followed a generalized protocol. However, the advent of personalized
medicine has ushered in a transformative era—one where periodontal therapy is tailored to the individual patient.
Personalized periodontics integrates patient-specific data including genetics, systemic health status, behavioral factors, and
risk profile to optimize diagnosis, prevention, and treatment outcomes. This article provides an overview of the P4 medicine
framework—predictive, preventive, personalized, and participatory—and illustrates how it is applied in periodontology.
Through the lens of key risk factors such as smoking, diabetes, obesity, cardiovascular disease, and stress, this review
emphasizes the need for individualized care pathways to enhance treatment efficacy and improve overall patient wellbeing.
Keywords :
Cardiovascular Disease, Diabetes, Obesity, Personalized Medicine, Periodontitis, Risk Stratification, Smoking, Stress.
References :
- Hood L. P4 medicine: personalized, predictive, preventive and participatory. OMICS. 2011;15(3):123–25.
- Preshaw PM, Alba AL, Herrera D, et al. Periodontitis and diabetes: a two-way relationship. Diabetologia. 2012;55(1):21–31.
- Tonetti MS, Jepsen S, Jin L, Otomo-Corgel J. Impact of the global burden of periodontal diseases on health, nutrition and wellbeing. J Clin Periodontol. 2017;44(5):456–62.
- Linden GJ, Herzberg MC. Periodontitis and systemic diseases: a record of discussions of working group 4 of the Joint EFP/AAP Workshop. J Periodontol. 2013;84(4-s):S20–S23.
- Van Dyke TE, Dave S. Risk factors for periodontitis. J Int Acad Periodontol. 2005;7(1):3–7.
Periodontal disease is a chronic, multifactorial condition that affects a significant portion of the global population.
Traditional approaches to its management have often followed a generalized protocol. However, the advent of personalized
medicine has ushered in a transformative era—one where periodontal therapy is tailored to the individual patient.
Personalized periodontics integrates patient-specific data including genetics, systemic health status, behavioral factors, and
risk profile to optimize diagnosis, prevention, and treatment outcomes. This article provides an overview of the P4 medicine
framework—predictive, preventive, personalized, and participatory—and illustrates how it is applied in periodontology.
Through the lens of key risk factors such as smoking, diabetes, obesity, cardiovascular disease, and stress, this review
emphasizes the need for individualized care pathways to enhance treatment efficacy and improve overall patient wellbeing.
Keywords :
Cardiovascular Disease, Diabetes, Obesity, Personalized Medicine, Periodontitis, Risk Stratification, Smoking, Stress.
