Numerous literature assessments have shown
that periodontitis, despite inducing local inflammation,
can also cause diverse systemic effects, similarly presence
of any systemic conditions such as diabetes mellitus,
hypertension, hematological diseases, cardiovascular
disease, respiratory disorders, endocrine disorders, etc.
can individually or collectively attribute to local
inflammatory reaction resulting in complete loss of teeth
and its associated structures. Among these systemic
factors hematological disorders are uncommon and rare
disorders that demonstrate non-specific oral and
periodontal manifestations. The present review was
undertaken to discuss briefly on the impact and role of
various hematological disorders manifesting with
substantial periodontal disease.
Keywords : Anemia, Cellular infiltration, Inflammation, Leukemia, Polymorphonuclear leukocytes, Tooth loss.