One-Pot Multicomponent Ultrasound Irradiated Synthesis of Heterocyclic Pyrimidines and Their Microbial Assay


Authors : Lekhni Sharma; Prakash C. Choudhary

Volume/Issue : Volume 6 - 2021, Issue 9 - September

Google Scholar : http://bitly.ws/gu88

Multicomponent reactions (MCR’s) play an important role in the synthetic chemistry. It enables the synthesis of small drug like molecules with many degree of structural viability. Use of green alternatives for this type of synthesis is the demand. Therefore, we developed an ecofriendly method using USI and flyash support Ba(OH)2 as catalyst. 18 molecules of 2-substituted-4,6- diheteroaryl pyrimidines were prepared by this method. The antibacterial screening against different pathogens were also studied and found compounds 3f and 3m as most effective one.

Keywords : Liquidity ratio, Solvency, Activity, Profitability, Market Value and Stock Returns

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