Authors :
Needish Joseph; Ritika Shetty; Nakshatra Shetty; Bhargabi Paul Majumder; Karthik Kumar; Rithesh K.B; Meghana HC; Raghavendra Kini; Nithin Gonsalves
Volume/Issue :
Volume 7 - 2022, Issue 6 - June
Google Scholar :
https://bit.ly/3IIfn9N
Scribd :
https://bit.ly/3a6t5rT
DOI :
https://doi.org/10.5281/zenodo.6791715
Abstract :
Odontogenic keratocyst (OKC) is a
developmental, non-inflammatory, chronic cystic lesion
of odontogenic origin which is considered aggressive due
to its genetic abnormalities and biological behavior being
consistent with neoplastic progression. OKC clinically
appears as a swelling with or without pain, occurring in
the jaw bones with greater predilection towards
mandible. Radiographically appearing as unicystic or
multicystic radiolucency with anteroposterior growth of
the lesion in the medullary spaces. Histologically the
presence of parakeratin and the ‘picket fence’ appearance
of the basal cell layer is unique to this lesion. Various
treatment modalities have been put forth but no specific
treatment has been regarded as the best. The goal of this
paper is to create awareness about the aggressive nature
of the OKC and to throw a light on its management.
Keywords :
OKC, Multicystic, Mandible, Dentigerous Cyst, Aggressive
Odontogenic keratocyst (OKC) is a
developmental, non-inflammatory, chronic cystic lesion
of odontogenic origin which is considered aggressive due
to its genetic abnormalities and biological behavior being
consistent with neoplastic progression. OKC clinically
appears as a swelling with or without pain, occurring in
the jaw bones with greater predilection towards
mandible. Radiographically appearing as unicystic or
multicystic radiolucency with anteroposterior growth of
the lesion in the medullary spaces. Histologically the
presence of parakeratin and the ‘picket fence’ appearance
of the basal cell layer is unique to this lesion. Various
treatment modalities have been put forth but no specific
treatment has been regarded as the best. The goal of this
paper is to create awareness about the aggressive nature
of the OKC and to throw a light on its management.
Keywords :
OKC, Multicystic, Mandible, Dentigerous Cyst, Aggressive