Authors : Devendra Kumar Singh; Bipin Bahadur Saxena; Vipin Kumar Singh

Volume/Issue : Volume 11 - 2026, Issue 7 - July

Google Scholar : https://tinyurl.com/yhms2a9m

Scribd : https://tinyurl.com/2ff3by89

DOI : https://doi.org/10.38124/ijisrt/26jul1822

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

Abstract : In the current study, metal ions of Co (III), Zn (II), Cu (II), Ni (II), and Schiff base ligand have been synthesized using a 1:1 molar ratio (3L:M), and (2L:M). To confirm the metal (II) complexes were effectively synthesized, the compound was characterized through UV-Vis, LC-MS, FTIR, elemental analysis, EDX, magnetic susceptibility measurement, and 1HNMR. Its molar conductance confirmed the non-ionic nature of the Co (III), Ni (II), Cu (II), and Zn (II) metal complexes. For these complexes, an octahedral geometry for the Co (III), a square planar geometry for the Cu (II) and Ni(II), and a tetrahedral geometry for the Zn (II) metal complexes have been suggested based on the data displayed. The examined chemicals in vitro biological screening effects were evaluated with respect to the antimicrobial species Klebsiella pneumoniae-7, Klebsiella pneumoniae, Escherichia coli, Proteus mirabilis, Citrobacter amalonaticus, Pseudomonas aeruginosa, Proteus mirabilis-7, Klebsiella pneumoniae, Escherichia coli- 10, and Citrobacter diversus-2, microorganisms species genera, Escherichia Pseudomonas, Citrobacter, Klebsiella and Proteus, and M. tuberculosis species by the agar well diffusion method. A comparison of the inhibitory values of the Schiff base ligands and their metal complexes shows that the complexes have more antituberculous action than the Schiff base ligand. The growth-inhibitor effect has been shown to depend on the metal ions. The initial cell density and the growth medium seemed to have a significant impact on the amount of inhibition.

Keywords : Schiff Base Ligand, Metal Complexes, FTIR, NMR and Antitubercular Activity”.

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