Authors :
Hardik Sharma; Shrutikant Bhatia; Kushal Rawal; Vandana Thakur
Volume/Issue :
Volume 9 - 2024, Issue 8 - August
Google Scholar :
https://tinyurl.com/yfysar75
Scribd :
https://tinyurl.com/5c2zhub7
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24AUG881
Abstract :
Malignancies known as neuroendocrine
neoplasms (NENs) have sporadic instances of developing
central nervous system. It was discovered that a 36-year-
old lady had a primary Neuroendocrine tumor of the
brain who presented with headache, vomiting, and
hearing difficulty from the left ear and was diagnosed
with a left cerebellopontine angle solid mass. After
subtotal excision, histology revealed a Neuroendocrine
tumor-II. Adjuvant radiation was administered
following a thorough search for an extracranial main
tumour, which included the use of Ga-68 DOTANOC-
PET-CT. This led to the identification of a primary
central nervous system Neuroendocrine tumor. The
patient was free of metastatic or recurrent disease at 9
months of follow-up.
Keywords :
Neuroendocrine Tumor; Cerebello-Pontine Angle; Radiotherapy, Subtotal Excision.
References :
- Reed CT, Duma N, Halfdanarson T, Buckner J. Primary neuroendocrine carcinoma of the brain. BMJ Case Rep. 2019 Sep 18;12(9):e230582.
- Greenberg K, Thomas J, Lopez A. Primary Neuroendocrine Tumor Of The Brain: Is It Becoming More Common? Int J Med Rev Case Rep. 2020;(0):1.
- Audlin JR, Khullar G, Deshaies EM, Kurra S, Lavelle WF. Intradural Carcinoid Tumor Found in a Patient with No History of Cancer. World Neurosurg. 2016 Dec;96:607.e1-607.e6.
- Kyriakopoulos G, Mavroeidi V, Chatzellis E, Kaltsas GA, Alexandraki KI. Histopathological, immunohistochemical, genetic and molecular markers of neuroendocrine neoplasms. Ann Transl Med. 2018 Jun;6(12):252.
- Satturwar SP, Pantanowitz JL, Manko CD, Seigh L, Monaco SE, Pantanowitz L. Ki-67 proliferation index in neuroendocrine tumors: Can augmented reality microscopy with image analysis improve scoring? Cancer Cytopathology. 2020;128(8):535–44.
- Sanli Y, Garg I, Kandathil A, Kendi T, Zanetti MJB, Kuyumcu S, et al. Neuroendocrine Tumor Diagnosis and Management: 68Ga-DOTATATE PET/CT. American Journal of Roentgenology. 2018 Aug 1;211(2):267–77.
- Tamura R, Kuroshima Y, Nakamura Y. Primary Neuroendocrine Tumor in Brain. Case Reports in Neurological Medicine. 2014 Nov 20;2014:e295253.
- Vernieri C, Femia D, Pusceddu S, Capella C, Rosai J, Calareso G, et al. Primary Cerebellar Neuroendocrine Tumors: Chimeras or Real Entities A Case Report with a 6-Year Follow-Up. CRO. 2016;9(2):432–9.
Malignancies known as neuroendocrine
neoplasms (NENs) have sporadic instances of developing
central nervous system. It was discovered that a 36-year-
old lady had a primary Neuroendocrine tumor of the
brain who presented with headache, vomiting, and
hearing difficulty from the left ear and was diagnosed
with a left cerebellopontine angle solid mass. After
subtotal excision, histology revealed a Neuroendocrine
tumor-II. Adjuvant radiation was administered
following a thorough search for an extracranial main
tumour, which included the use of Ga-68 DOTANOC-
PET-CT. This led to the identification of a primary
central nervous system Neuroendocrine tumor. The
patient was free of metastatic or recurrent disease at 9
months of follow-up.
Keywords :
Neuroendocrine Tumor; Cerebello-Pontine Angle; Radiotherapy, Subtotal Excision.