Neuro-Behcet’s Disease: A Case Report of a 19-Year-Old Male with Recurrent Aphthous Ulcers, Headache, and Neurological Deficit


Authors : Dr. Hanushanth G.; Dr. Rajendra Mali; Dr. Santosh Patil; Dr. Virupaxi Hattiholi; Dr. Pradeepgoud H. Patil; Dr. Pradeep Goudarkles

Volume/Issue : Volume 10 - 2025, Issue 3 - March


Google Scholar : https://tinyurl.com/4rrfhkpf

Scribd : https://tinyurl.com/zvx2rfut

DOI : https://doi.org/10.38124/ijisrt/25mar1446

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Abstract : Neuro-Behcet's disease (NBD) is a rare and challenging manifestation of Behcet's disease (BD) that involves the central nervous system (CNS), affecting less than 10% of BD patients. The clinical spectrum includes neurological deficits such as motor dysfunction, memory impairment, and personality changes, often presenting subacutely. Here, we report a case of a 19-year-old male presenting with recurrent aphthous ulcers, headache, irritability, and left-sided limb weakness. MRI findings revealed hyperintensities in the left corona radiata, bilateral basal ganglia, midbrain, and pons, characteristic of NBD. The patient's clinical and imaging findings were consistent with a diagnosis of Neuro-Behcet's disease.

References :

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Neuro-Behcet's disease (NBD) is a rare and challenging manifestation of Behcet's disease (BD) that involves the central nervous system (CNS), affecting less than 10% of BD patients. The clinical spectrum includes neurological deficits such as motor dysfunction, memory impairment, and personality changes, often presenting subacutely. Here, we report a case of a 19-year-old male presenting with recurrent aphthous ulcers, headache, irritability, and left-sided limb weakness. MRI findings revealed hyperintensities in the left corona radiata, bilateral basal ganglia, midbrain, and pons, characteristic of NBD. The patient's clinical and imaging findings were consistent with a diagnosis of Neuro-Behcet's disease.

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