Authors :
Dr Chandra Sekhar Mohapatra; Dr. Shilpa Pande; Shreesh Jain; Panamareddy Bhavitha; Sharad Vyankatrao Mali; Dr. Chahat Shikarwar
Volume/Issue :
Volume 8 - 2023, Issue 5 - May
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://t.ly/_Q5e
DOI :
https://doi.org/10.5281/zenodo.7992780
Abstract :
Nanotechnology is emerging as new
implementations that can be used directly or indirectly
to combat lethal bacterial infections & surmount
antibiotic resistance. Antibiotic overuse is on the rise due
to factors including an ageing population, a rise in
infectious illnesses, & the frequency of chronic
conditions that need their treatment. The broad
distribution of resistance genes at an environmental scale
may be traced back to the extra & inadvisable utilisation
of antibiotics by humans, which has led to the rise of
bacteria resistance to existing antibiotics & the selective
growth of other microbes. The widespread dissemination
of resistance & the transfer of resistance genes across
bacterial species resulted in the appearance of
multidrug-resistant (MDR) pathogens. This concern is
exacerbated by the formation of biofilms by
microorganisms, which can increase bacterial resistance
by up to a factor of 1,000 & promote a rise of MDR
infections. Therefore, the purpose of the study is to
review nanotechnology as a potential method for
combating MDR bacteria: a comprehensive analysis &
future prospects. The methodologies are discussed based
on secondary sources (websites, Google Scholar &
various internet sources). This research demonstrated
that AgNPs are extremely potent nanoparticles (NPs) for
the treatment of MDR bacteria. Antibacterial activity of
Ag NPs was shown, & their efficacy against MDR
bacteria was confirmed. In conclusion, the biosynthesis
of pure Ag NPs with significant antibacterial MDR
action seems to be a step in the right direction, thanks to
this innovative approach.
Keywords :
Multi Drug Resistant Bacteria, Antibacterial Activity, Nanotechnology.
Nanotechnology is emerging as new
implementations that can be used directly or indirectly
to combat lethal bacterial infections & surmount
antibiotic resistance. Antibiotic overuse is on the rise due
to factors including an ageing population, a rise in
infectious illnesses, & the frequency of chronic
conditions that need their treatment. The broad
distribution of resistance genes at an environmental scale
may be traced back to the extra & inadvisable utilisation
of antibiotics by humans, which has led to the rise of
bacteria resistance to existing antibiotics & the selective
growth of other microbes. The widespread dissemination
of resistance & the transfer of resistance genes across
bacterial species resulted in the appearance of
multidrug-resistant (MDR) pathogens. This concern is
exacerbated by the formation of biofilms by
microorganisms, which can increase bacterial resistance
by up to a factor of 1,000 & promote a rise of MDR
infections. Therefore, the purpose of the study is to
review nanotechnology as a potential method for
combating MDR bacteria: a comprehensive analysis &
future prospects. The methodologies are discussed based
on secondary sources (websites, Google Scholar &
various internet sources). This research demonstrated
that AgNPs are extremely potent nanoparticles (NPs) for
the treatment of MDR bacteria. Antibacterial activity of
Ag NPs was shown, & their efficacy against MDR
bacteria was confirmed. In conclusion, the biosynthesis
of pure Ag NPs with significant antibacterial MDR
action seems to be a step in the right direction, thanks to
this innovative approach.
Keywords :
Multi Drug Resistant Bacteria, Antibacterial Activity, Nanotechnology.