Authors :
Venkatesh T Lamani; B S Raviteja; L Lokesh Kumar; Ashish S V; Arun A
Volume/Issue :
Volume 6 - 2021, Issue 12 - December
Google Scholar :
http://bitly.ws/gu88
Scribd :
https://bit.ly/3qj7TEd
Abstract :
The primary aim of this research was to
evaluate the use of ferromagnetic nano particles and the
use of the AC magnetic field for the treatment of cancer
cells by the process of Hyperthermia. The major
drawback of conventional methods for treating cancer
(chemotherapy/ radiation therapy) is that it is timeconsuming and not always are results guaranteed. The
process is highly efficient as the nano particles generate
heat locally thus preventing any damage to the
surrounding healthy tissues. Also, the nano particles
possess the potential to act as contrast agents for
magnetic resonance imaging (MRI) making it easier to
monitor the process. We try to reduce the procedure
time by the introduction of magnetic nano particles
which readily react to an external alternating magnetic
field. This enables the nano particles to heat up to a
temperature sufficient enough for tumor cell necrosis
(>50deg C). The temperature spread in the tissue is
studied using a COMSOL™ based Multi physics model
(based on combining the Laplace, Arrhenius model and
bio-heat transfer (BHTE) equation) customized for the
ablation device geometry and boundary conditions. The
results obtained are compared and found to be in good
agreement with published text.
Keywords :
AC Magnetic field; COMSOL Multi physics; Hyperthermia; Nano particles
The primary aim of this research was to
evaluate the use of ferromagnetic nano particles and the
use of the AC magnetic field for the treatment of cancer
cells by the process of Hyperthermia. The major
drawback of conventional methods for treating cancer
(chemotherapy/ radiation therapy) is that it is timeconsuming and not always are results guaranteed. The
process is highly efficient as the nano particles generate
heat locally thus preventing any damage to the
surrounding healthy tissues. Also, the nano particles
possess the potential to act as contrast agents for
magnetic resonance imaging (MRI) making it easier to
monitor the process. We try to reduce the procedure
time by the introduction of magnetic nano particles
which readily react to an external alternating magnetic
field. This enables the nano particles to heat up to a
temperature sufficient enough for tumor cell necrosis
(>50deg C). The temperature spread in the tissue is
studied using a COMSOL™ based Multi physics model
(based on combining the Laplace, Arrhenius model and
bio-heat transfer (BHTE) equation) customized for the
ablation device geometry and boundary conditions. The
results obtained are compared and found to be in good
agreement with published text.
Keywords :
AC Magnetic field; COMSOL Multi physics; Hyperthermia; Nano particles
