Nanoparticles use for the Effective Hyperthermia of Liver Tumor


Authors : Venkatesh T Lamani; B S Raviteja; L Lokesh Kumar; Ashish S V; Arun A

Volume/Issue : Volume 6 - 2021, Issue 12 - December

Google Scholar : http://bitly.ws/gu88

Scribd : https://bit.ly/3qj7TEd

The primary aim of this research was to evaluate the use of ferromagnetic nano particles and the use of the AC magnetic field for the treatment of cancer cells by the process of Hyperthermia. The major drawback of conventional methods for treating cancer (chemotherapy/ radiation therapy) is that it is timeconsuming and not always are results guaranteed. The process is highly efficient as the nano particles generate heat locally thus preventing any damage to the surrounding healthy tissues. Also, the nano particles possess the potential to act as contrast agents for magnetic resonance imaging (MRI) making it easier to monitor the process. We try to reduce the procedure time by the introduction of magnetic nano particles which readily react to an external alternating magnetic field. This enables the nano particles to heat up to a temperature sufficient enough for tumor cell necrosis (>50deg C). The temperature spread in the tissue is studied using a COMSOLâ„¢ based Multi physics model (based on combining the Laplace, Arrhenius model and bio-heat transfer (BHTE) equation) customized for the ablation device geometry and boundary conditions. The results obtained are compared and found to be in good agreement with published text.

Keywords : AC Magnetic field; COMSOL Multi physics; Hyperthermia; Nano particles

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