Molecular Prevalence of Pulmonary Tuberculosis in Prisons: Case of the Central Prison of Franceville


Authors : Bourdettes Meye; Guy Roger Ndong Atome; Cedric Sima Obiang; Hilaire Kenguele Moundounga; Thièry Ndong Mba; Dieudonné Nkoghe; Joseph Privat Ondo; Louis-Clément Obame Engonga

Volume/Issue : Volume 8 - 2023, Issue 6 - June

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://tinyurl.com/42jkvsuu

DOI : https://doi.org/10.5281/zenodo.8170673

Abstract : Background: In Gabon, the epidemic of pulmonary tuberculosis (TB) in prisons is poorly documented. There is no official data, even though these environments meet the perfect conditions for transmission of the disease: overcrowding, close and prolonged contact, and the inexistence of a policy of screening/medical check-up of inmates upon their admission to prison. The objective of this study was to conduct a prospective and cross- sectional study to assess the prevalence of pulmonary tuberculosis in the prison environment of Yéné, the central prison of Franceville, capital of the Haut-Ogooué province. Methods: A preliminary clinical survey of inmates identified a cohort of 100 individuals suspected of having TB based on clinical symptoms. Subsequently, from June 9 to 13, 2022, we collected sputum samples from inmates suspected of having TB. These samples were analyzed by the molecular biology technique GeneXpert MTB/RIF.Conclusion: In Yéné prison, the non-existence of diagnostic tests for TB to newly incarcerated inmates puts other inmates as well as prison officers at risk for TB infection.

Keywords : Mycobacterium tuberculosis, Tuberculosis, GeneXpert, prison environment, Haut-Ogooué.

Background: In Gabon, the epidemic of pulmonary tuberculosis (TB) in prisons is poorly documented. There is no official data, even though these environments meet the perfect conditions for transmission of the disease: overcrowding, close and prolonged contact, and the inexistence of a policy of screening/medical check-up of inmates upon their admission to prison. The objective of this study was to conduct a prospective and cross- sectional study to assess the prevalence of pulmonary tuberculosis in the prison environment of Yéné, the central prison of Franceville, capital of the Haut-Ogooué province. Methods: A preliminary clinical survey of inmates identified a cohort of 100 individuals suspected of having TB based on clinical symptoms. Subsequently, from June 9 to 13, 2022, we collected sputum samples from inmates suspected of having TB. These samples were analyzed by the molecular biology technique GeneXpert MTB/RIF.Conclusion: In Yéné prison, the non-existence of diagnostic tests for TB to newly incarcerated inmates puts other inmates as well as prison officers at risk for TB infection.

Keywords : Mycobacterium tuberculosis, Tuberculosis, GeneXpert, prison environment, Haut-Ogooué.

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