Authors :
D. Nagavalli; M. Gokulkannan; S. Gurunathan; V. Manikandan; V. Kamesh; N. Poongundran
Volume/Issue :
Volume 8 - 2023, Issue 9 - September
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/2yzrhnfs
DOI :
https://doi.org/10.5281/zenodo.8376355
Abstract :
One of the most crucial and complex processes
is the skin's multi-stage process of healing after an injury.
Heliotropium indicum is a potent antibiotic, anti-
inflammatory, anti-neoplastic, anti-oxidant, and wound-
healing agent. Heliotropium indicum Linn is the source of
the chemical compound in question, which is abundant in
sterols, ammines, volatile oils, and the pyrrolizidine
alkaloids. Molecular docking studies were conducted on
Heliotropium indicum using Argus lab 4.0.1 and
Autodock 1.5.7. The proteins PDB ID:1YXO, 3V18, and
4G8R were selected because of their role in wound
healing. The pieces work together with the protein
responsible for mending wounds. The binding affinities of
mupirocin and nitrofurazone are higher than those of the
components stigmasterol, eugenol, borneol, and
campesterol. In order to better customize Heliotropium
indicum to our requirements, we now have a better
knowledge of the components of the molecule that
interact with their receptors in the wound healing
process.
Keywords :
Docking, Heliotropium Indicum, Wound Healing, Software’s.
One of the most crucial and complex processes
is the skin's multi-stage process of healing after an injury.
Heliotropium indicum is a potent antibiotic, anti-
inflammatory, anti-neoplastic, anti-oxidant, and wound-
healing agent. Heliotropium indicum Linn is the source of
the chemical compound in question, which is abundant in
sterols, ammines, volatile oils, and the pyrrolizidine
alkaloids. Molecular docking studies were conducted on
Heliotropium indicum using Argus lab 4.0.1 and
Autodock 1.5.7. The proteins PDB ID:1YXO, 3V18, and
4G8R were selected because of their role in wound
healing. The pieces work together with the protein
responsible for mending wounds. The binding affinities of
mupirocin and nitrofurazone are higher than those of the
components stigmasterol, eugenol, borneol, and
campesterol. In order to better customize Heliotropium
indicum to our requirements, we now have a better
knowledge of the components of the molecule that
interact with their receptors in the wound healing
process.
Keywords :
Docking, Heliotropium Indicum, Wound Healing, Software’s.
