Authors :
Ashwini. J; Swathi. K; Anitha. S; Dr. T. Suchitra Naidu; A. Jaya Madhuri Lata
Volume/Issue :
Volume 7 - 2022, Issue 4 - April
Google Scholar :
https://bit.ly/3IIfn9N
Scribd :
https://bit.ly/3ziwFcw
DOI :
https://doi.org/10.5281/zenodo.6614394
Abstract :
Micro RNA is a small non coding conserved
ssRNA, which helps in regulating gene expression.
miRNA are being used in the pathogenesis of various
human diseases like cancer, neurological disorders, and
in other infectious diseases. miRNA are typically short of
17-25 nucleotides which are known to affect the
messenger RNA, affecting the translation thereby
regulating the gene.
In plants, the mature miRNA enters an RNA
induced Silencing Complex called RISC, negatively
regulating the gene expression. Nowadays these miRNA
are being used to silence the genes which are not essential
for the survival of plants, so that the other beneficial
genes like the drought resistance, salt tolerance, immunity
and vitamin inducing genes can be regulated.
In the present, research we tried to get the mi RNA
of the already sequenced plant strain using miRNA
database, comparison was done to find the similarities
amongst the two strains and then miRNA-protein
docking was done. It was found that MAP KINASE gene
and Osa-MIR1862a an mi RNA can be docked. subject to
experimental verification.
Micro RNA is a small non coding conserved
ssRNA, which helps in regulating gene expression.
miRNA are being used in the pathogenesis of various
human diseases like cancer, neurological disorders, and
in other infectious diseases. miRNA are typically short of
17-25 nucleotides which are known to affect the
messenger RNA, affecting the translation thereby
regulating the gene.
In plants, the mature miRNA enters an RNA
induced Silencing Complex called RISC, negatively
regulating the gene expression. Nowadays these miRNA
are being used to silence the genes which are not essential
for the survival of plants, so that the other beneficial
genes like the drought resistance, salt tolerance, immunity
and vitamin inducing genes can be regulated.
In the present, research we tried to get the mi RNA
of the already sequenced plant strain using miRNA
database, comparison was done to find the similarities
amongst the two strains and then miRNA-protein
docking was done. It was found that MAP KINASE gene
and Osa-MIR1862a an mi RNA can be docked. subject to
experimental verification.
