Micro RNA-Gene Docking in the Strains of Oryza Sativa

Authors : Ashwini. J; Swathi. K; Anitha. S; Dr. T. Suchitra Naidu; A. Jaya Madhuri Lata

Volume/Issue : Volume 7 - 2022, Issue 4 - April

Google Scholar : https://bit.ly/3IIfn9N

Scribd : https://bit.ly/3ziwFcw

DOI : https://doi.org/10.5281/zenodo.6614394

Micro RNA is a small non coding conserved ssRNA, which helps in regulating gene expression. miRNA are being used in the pathogenesis of various human diseases like cancer, neurological disorders, and in other infectious diseases. miRNA are typically short of 17-25 nucleotides which are known to affect the messenger RNA, affecting the translation thereby regulating the gene. In plants, the mature miRNA enters an RNA induced Silencing Complex called RISC, negatively regulating the gene expression. Nowadays these miRNA are being used to silence the genes which are not essential for the survival of plants, so that the other beneficial genes like the drought resistance, salt tolerance, immunity and vitamin inducing genes can be regulated. In the present, research we tried to get the mi RNA of the already sequenced plant strain using miRNA database, comparison was done to find the similarities amongst the two strains and then miRNA-protein docking was done. It was found that MAP KINASE gene and Osa-MIR1862a an mi RNA can be docked. subject to experimental verification.


Paper Submission Last Date
31 - December - 2023

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