Authors : Dr. Kunal Tejnani; Dr. Khalid Agwani; Dr. Srishti Mishra; Dr. Ramank Mathur; Dr. Pooja Ghosh; Dr. Nayan Joshi; Dr. Dishantkumar Sonpal

Volume/Issue : Volume 10 - 2025, Issue 12 - December

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Google Scholar : https://tinyurl.com/32cpn6h4

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DOI : https://doi.org/10.38124/ijisrt/25dec255

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Abstract : This Review of Literature examines the role of melatonin in pain and anxiety management following impacted mandibular third molar surgery. Impacted third molar surgeries are often associated with unpleasant post-operative sequalae such as pain and anxiety. The mainstay of conventional pharmacological management includes NSAIDs, opioids, and benzodiazepines which carry certain side-effects. Melatonin, an endogenous hormone with antioxidant, anti- inflammatory, and neuromodulatory properties, has been proposed as a promising and safe perioperative adjuvant. The aim of this literature review is to evaluate the efficacy of Melatonin on postoperative pain and preoperative anxiety, gather current evidence on its pharmacological mechanisms and to compare it against existing pharmacological agents

Keywords : Melatonin, Analgesia, Anxiolytic, Third Molar Surgery.

References :

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