Management Approaches in Corneal Keratoconus


Authors : Koppula Divya; Dr. A. Srinivasa Rao; Dr. AV Kishore Babu; P. Divyani; L. Anjali

Volume/Issue : Volume 8 - 2023, Issue 8 - August

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://tinyurl.com/y9y3ned5

DOI : https://doi.org/10.5281/zenodo.8328759

Abstract : Corneal Keratoconus is a disease characterised by gradual thinning of central and peripheral stroma resulting in protrusion and reduced visual activity. The aetiology of keratoconus is an underlying genetic predisposition coupled with environmental factors, including eye rubbing and atopy. Spectacles, contact lens and Intrastromal Corneal Ring Segments (ICRS) remain fundamental to optic management of keratoconus. These contact lens and ICRS do not treat underlying disease process. Keratoplasty – Penetrating Keratoplasty (PK), deep anterior lamellar keratoplasty (DALK) treatment of choice for advance form of keratoconus. Therefore, current approach is corneal collagen cross-linking (CXL). CXL aims at stiffing the cornea using a combination of UV-A light and chromophore (Vit-B12, riboflavin) and proposed in various indications, from progressive ecstatic disease to corneal infection.

Keywords : Best Corrected Visual Acuity (BCVA), Spectacles and Contact Lens (SCL), Intrastromal Corneal Ring Segment (ICRS), Conservative, Intermediate and Advanced Treatment, Keratoplasty -PK, DALK, Corneal Collagen Cross Linking (CXL).

Corneal Keratoconus is a disease characterised by gradual thinning of central and peripheral stroma resulting in protrusion and reduced visual activity. The aetiology of keratoconus is an underlying genetic predisposition coupled with environmental factors, including eye rubbing and atopy. Spectacles, contact lens and Intrastromal Corneal Ring Segments (ICRS) remain fundamental to optic management of keratoconus. These contact lens and ICRS do not treat underlying disease process. Keratoplasty – Penetrating Keratoplasty (PK), deep anterior lamellar keratoplasty (DALK) treatment of choice for advance form of keratoconus. Therefore, current approach is corneal collagen cross-linking (CXL). CXL aims at stiffing the cornea using a combination of UV-A light and chromophore (Vit-B12, riboflavin) and proposed in various indications, from progressive ecstatic disease to corneal infection.

Keywords : Best Corrected Visual Acuity (BCVA), Spectacles and Contact Lens (SCL), Intrastromal Corneal Ring Segment (ICRS), Conservative, Intermediate and Advanced Treatment, Keratoplasty -PK, DALK, Corneal Collagen Cross Linking (CXL).

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