Authors : Anita Ismaili Bimbashi; Enis Redjep; Gazmend Jusufi; Elza Mucaj

Volume/Issue : Volume 11 - 2026, Issue 10 - October

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Google Scholar : https://tinyurl.com/4tuhw4hd

DOI : https://doi.org/10.38124/ijisrt/26Oct850

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

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Abstract : Background: Dental extraction in patients receiving direct oral anticoagulants requires careful bleeding-risk assessment and local hemostatic measures. Concomitant type 2 diabetes may further complicate postoperative care.

Keywords : Advanced Platelet-Rich Fibrin; A-PRF+; Rivaroxaban; Tranexamic Acid; Surgical Tooth Extraction; Case Report.

References :

1. Scottish Dental Clinical Effectiveness Programme. Management of Dental Patients Taking Anticoagulants or Antiplatelet Drugs. 2nd ed. Dundee: SDCEP; 2022. Available from: https://www.sdcep.org.uk/published-guidance/anticoagulants-and-antiplatelets/
2. Katz MS, Ooms M, Heitzer M, Steiner T, Bock A, Peters F, et al. Platelet-rich fibrin as a hemostatic agent in dental extractions in patients taking anticoagulants or antiplatelet medication: a systematic review. Clin Oral Investig. 2024;28:587. doi:10.1007/s00784-024-05983-x.
3. Cetira Filho EL, Franco JMPL, Ribeiro TR, Silva PGB, Costa FWG. Does platelet-rich fibrin prevent hemorrhagic complications after dental extractions in patients using oral anticoagulant therapy? J Oral Maxillofac Surg. 2021;79:2215–2226. doi:10.1016/j.joms.2021.07.003.
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6. Steffel J, Collins R, Antz M, Cornu P, Desteghe L, Haeusler KG, et al. 2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation. Europace. 2021;23(10):1612-1676. doi:10.1093/europace/euab065.
7. Douketis JD, Spyropoulos AC, Duncan J, Carrier M, Le Gal G, Tafur AJ, et al. Perioperative Management of Patients With Atrial Fibrillation Receiving a Direct Oral Anticoagulant. JAMA Intern Med. 2019;179(11):1469-1478. doi:10.1001/jamainternmed.2019.2431.