Authors :
Dr Kedar Kawsankar; Dr Harish Saluja; Dr Seemit Shah; Dr Anuj Dadhich; Dr Srishti Salunke; Dr Vinayak More; Dr Anuja Deshpande; Dr Megha Kiran
Volume/Issue :
Volume 8 - 2023, Issue 10 - October
Google Scholar :
https://tinyurl.com/m6bf2z7f
Scribd :
https://tinyurl.com/4y5yphka
DOI :
https://doi.org/10.5281/zenodo.10099196
Abstract :
Background:
Squamous cell carcinoma (OSCC) is one of the most
common malignancies of oral cavity. Metastasis of oral
squamous cell carcinoma (OSCC) is a complex process
involving detachment of cells from the tumor tissue,
regulation of cell motility and invasion, proliferation and
evasion through the lymphatic system or blood vessels.
The metastasis may affect the prognosis. 1Since not only the suppression of primary lesion but
also the presence or absence of metastasis in the cervical
lymph nodes may greatly influence the outcome of oral
cancer. 2, 3The submental lymph nodes are categories as Level
Ia lymph nodes. 4 Aim of present study was to evaluate
Level Ia lymph node metastasis in patients having oral
squamous cell carcinoma.Materials and methods:
The research was undertaken following approval
from the institutional ethics committee and spanned a
duration of two years, during which a comprehensive
evaluation was performed on 67 participants.Results:
Level Ia lymph node metastasis was 22.4% (15
patients). Among 22.4% patients with level Ia lymph
node metastasis, most common site of primary tumor
was lip (50%). T4b lesions showed highest prevalence in
patients with level Ia lymph node metastasis. Out of total
22.4% of level Ia lymph node metastasis, 13.04% (3
patients) patients had clinically N0 neck. On comparison
of final histopathological diagnosis with level Ia lymph
node metastasis, 50% cases diagnosed with poorly
differentiated squamous cell carcinoma. Metastasis at
level Ia was associated along with level Ib lymph node
metastasis (46.6%) followed by level IIa lymph node
metastasis (33.3%).Conclusion:
In conclusion, the present study depicted that level
Ia lymph node metastasis was significant. Hence, level Ia
lymph node dissection should be taken into the
consideration in patients with OSCC.
Background:
Squamous cell carcinoma (OSCC) is one of the most
common malignancies of oral cavity. Metastasis of oral
squamous cell carcinoma (OSCC) is a complex process
involving detachment of cells from the tumor tissue,
regulation of cell motility and invasion, proliferation and
evasion through the lymphatic system or blood vessels.
The metastasis may affect the prognosis. 1Since not only the suppression of primary lesion but
also the presence or absence of metastasis in the cervical
lymph nodes may greatly influence the outcome of oral
cancer. 2, 3The submental lymph nodes are categories as Level
Ia lymph nodes. 4 Aim of present study was to evaluate
Level Ia lymph node metastasis in patients having oral
squamous cell carcinoma.Materials and methods:
The research was undertaken following approval
from the institutional ethics committee and spanned a
duration of two years, during which a comprehensive
evaluation was performed on 67 participants.Results:
Level Ia lymph node metastasis was 22.4% (15
patients). Among 22.4% patients with level Ia lymph
node metastasis, most common site of primary tumor
was lip (50%). T4b lesions showed highest prevalence in
patients with level Ia lymph node metastasis. Out of total
22.4% of level Ia lymph node metastasis, 13.04% (3
patients) patients had clinically N0 neck. On comparison
of final histopathological diagnosis with level Ia lymph
node metastasis, 50% cases diagnosed with poorly
differentiated squamous cell carcinoma. Metastasis at
level Ia was associated along with level Ib lymph node
metastasis (46.6%) followed by level IIa lymph node
metastasis (33.3%).Conclusion:
In conclusion, the present study depicted that level
Ia lymph node metastasis was significant. Hence, level Ia
lymph node dissection should be taken into the
consideration in patients with OSCC.
