Authors :
Vahid Hosseini; Seyed Masoud Ghoreishi Mokri; Dalia hafezghoran; Bahareh Karimi; Anastasia Aleksandrovna Anashkina; Anna Borisovna Yazykova
Volume/Issue :
Volume 9 - 2024, Issue 5 - May
Google Scholar :
https://tinyurl.com/3debx63a
Scribd :
https://tinyurl.com/2hr9puej
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24MAY1087
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
The drug delivery systems that were used in the
past were done without any control over the time, place
and speed of drug release, and this caused the amount of
drug released in the blood to fluctuate, that is, the
concentration of the drug in the blood could vary from
The therapeutic range will be exceeded and its side effects
will also increase. Therefore, with targeted medicine, it is
possible to control the place of drug release, its speed and
time, and minimize the side effects caused by the drug. In
this regard, in this research, the natural hydrogel
extracted from the Plantago ovate plant as one of the drug
carriers in the body environment in order to increase the
efficiency and reduce the degradation of the drug, prevent
the side effects caused by the use of the drug and increase
the access to the drug and improve Its effect was
investigated at the lesion site. In this context, after
extracting the natural hydrogel from Plantago ovate
plant, the swelling rate of Plantago ovate gel powder was
investigated at different pH, the FT-IR spectrum obtained
from Plantago ovate hydrogel and the swelling rate of
Plantago ovate mucilage at different pH were
investigated. Therefore, the obtained results indicate that
natural polysaccharides can be used as a natural drug
carrier in drug delivery systems due to their high
biocompatibility in the body environment, non-toxicity
and cheapness.
Keywords :
Targeted Drug Delivery - Plantago Ovate Plant - Natural Hydrogel - Polymer Nanoparticles.
References :
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- Mokri SM, Valadbeygi N, Stelnikova IG. Using Convolutional Neural Network to Design and Predict the Forces and Kinematic Performance and External Rotation Moment of the Hip Joint in the Pelvis. International Journal of Innovative Science and Research Technology (IJISRT) IJISRT24FEB1059. 2024:878-83.
- Valadbeygi N. A Parametric Study to Predict Wind Energy Potential from Neural Network.
- Mokri SM, Valadbeygi N, Grigoryeva V. Diagnosis of Glioma, Menigioma and Pituitary brain tumor using MRI images recognition by Deep learning in Python. EAI Endorsed Transactions on Intelligent Systems and Machine Learning Applications. 2024 Apr 15;1.
- Valadbeygi N. Wet Cooling Tower Heat Transfer and Function Prediction using MLP Neural Network.
- Mokri SM, Valadbeygi N, Balyasimovich KM. Predicting the Performance and Adaptation of Artificial Elbow Due to Effective Forces using Deep Learning".
- Mokri SM, Valadbeygi N, Mohammed K. Physiological study of joint loaded force in the artificial knee with the neural approach.
- Valadbeygi N, Shahrjerdi A. Prediction of Heating Energy Consumption in Houses via Deep Learning Neural Network. Analytical and Numerical Methods in Mechanical Design. 2022 Dec 1;1(2):11-6.
- Hosseini V, Mokri SM, Viktorovna KA. Targeted Drug Delivery through the Synthesis of Magnetite Nanoparticle by Co-Precipitation Method and Creating a Silica Coating on it.
The drug delivery systems that were used in the
past were done without any control over the time, place
and speed of drug release, and this caused the amount of
drug released in the blood to fluctuate, that is, the
concentration of the drug in the blood could vary from
The therapeutic range will be exceeded and its side effects
will also increase. Therefore, with targeted medicine, it is
possible to control the place of drug release, its speed and
time, and minimize the side effects caused by the drug. In
this regard, in this research, the natural hydrogel
extracted from the Plantago ovate plant as one of the drug
carriers in the body environment in order to increase the
efficiency and reduce the degradation of the drug, prevent
the side effects caused by the use of the drug and increase
the access to the drug and improve Its effect was
investigated at the lesion site. In this context, after
extracting the natural hydrogel from Plantago ovate
plant, the swelling rate of Plantago ovate gel powder was
investigated at different pH, the FT-IR spectrum obtained
from Plantago ovate hydrogel and the swelling rate of
Plantago ovate mucilage at different pH were
investigated. Therefore, the obtained results indicate that
natural polysaccharides can be used as a natural drug
carrier in drug delivery systems due to their high
biocompatibility in the body environment, non-toxicity
and cheapness.
Keywords :
Targeted Drug Delivery - Plantago Ovate Plant - Natural Hydrogel - Polymer Nanoparticles.