Authors :
KENEILWE KENNY KAUDIMBA, ARNAUD CEDRICK PICKA MISSENGUE, RU WANG
Volume/Issue :
Volume 6 - 2021, Issue 9 - September
Google Scholar :
http://bitly.ws/gu88
Scribd :
https://bit.ly/2XT0rDU
Abstract :
Leptin, a white adipose secreted hormone,
plays a central part within the control of nourishment
admissions and vitality use, whereas Leptin mutation
gene effects in congenital leptin deficiency (CLD), which
leads to leptin deficiency. Therefore, there is a lack of
circulating leptin, resulting in extreme obesity, severe
overeating, and severe metabolic abnormalities. The
physiological and pathophysiological parts of leptin in
weight have been explored broadly since its revelation in
1994. However, the pathophysiological aspects of leptin
or leptin receptor mutations as to how it causes hepatic
steatosis and severe obesity has not been well explained.
Hence, this submission aims to describe leptin and
outline how it is associated with congenital leptin
deficiency.
Keywords :
Leptin, Congenital Leptin Deficiency, Lepbr, Obesity, Exercise and Leptin Mutation.
Leptin, a white adipose secreted hormone,
plays a central part within the control of nourishment
admissions and vitality use, whereas Leptin mutation
gene effects in congenital leptin deficiency (CLD), which
leads to leptin deficiency. Therefore, there is a lack of
circulating leptin, resulting in extreme obesity, severe
overeating, and severe metabolic abnormalities. The
physiological and pathophysiological parts of leptin in
weight have been explored broadly since its revelation in
1994. However, the pathophysiological aspects of leptin
or leptin receptor mutations as to how it causes hepatic
steatosis and severe obesity has not been well explained.
Hence, this submission aims to describe leptin and
outline how it is associated with congenital leptin
deficiency.
Keywords :
Leptin, Congenital Leptin Deficiency, Lepbr, Obesity, Exercise and Leptin Mutation.
