Human saliva is incredibly a versatile organic
fluid. Its collection is easy and non-invasive. The
biomarkers present in the saliva prove themselves to be
of diagnostic and prognostic importance for oral diseases
like, periodontitis, oral lichen planus and oral
leukoplakia. These biomarkers include growth factors,
enzymes and interleukins. They also help in diagnosis of
these diseases and for evaluation of risk of malignancy,
monitoring of disease and the response to provided
treatment. However, more research are required to
discover biomarkers and verification of their diagnostic
and prognostic role in context with oral diseases is
needed. This article review a complete and thorough
assessment of importance of saliva as a diagnostic device
for the potential diagnosis of oral and systemic disease.
Keywords : Saliva, Salivary biomarkers, Systemic disease, Cytokines, Genes.