Authors :
Olawuyi T. S; Oluwasina O. O; Akinola B. K; Taiwo J. A
Volume/Issue :
Volume 6 - 2021, Issue 12 - December
Google Scholar :
http://bitly.ws/gu88
Scribd :
https://bit.ly/3qp4LXa
Abstract :
This study aimed at the ameliorating effect of
composite teas on aluminum-induced testicular-toxicity
of adult male Wistar rats. Thirty adults male Wistar rats
of average body weight of 100-180g, divided into 6 groups
with Five (5) rats per group were used. Administration of
aluminum chloride (AlCl3) was given for 2weeks, followed
by composite tea administered orally for two (2) weeks.
Group 1 received 0.15mg/kg of AlCl3, Group 2 (control)
received feed pellets and distilled water. Groups 3, 4, 5 &
6 received 0.15mg/kg AlCl3 and 5mg/kg of composite tea
respectively. Twenty-four hours after last administration,
the animals were weighed, sedated with diethy-ether in a
chamber, and blood was collected. The testes were excised
and weighed. There were statistically significant
alterations in the percentage of seminiferous tubular and
seminiferous ductal diameter within the animals in all the
groups (p<0.05). Significant changes in sperm
parameters, hormone profiles and defective testicular
morphology in Groups 1, 3, 4 when compared to the
control group. However significant improvements were
noticed in Group 6 after administration of composite tea,
with restored sperm characteristics, restored hormonal
assessments and preserved testicular structures.
Conclusively, the ameliorating effect of the composite teas
were revealed on aluminum-induced toxicity of adult
Wistar rat.
Keywords :
Male Infertilty, Histomorphometry, Composite Teas, Aluminium, Testicular Toxicity
This study aimed at the ameliorating effect of
composite teas on aluminum-induced testicular-toxicity
of adult male Wistar rats. Thirty adults male Wistar rats
of average body weight of 100-180g, divided into 6 groups
with Five (5) rats per group were used. Administration of
aluminum chloride (AlCl3) was given for 2weeks, followed
by composite tea administered orally for two (2) weeks.
Group 1 received 0.15mg/kg of AlCl3, Group 2 (control)
received feed pellets and distilled water. Groups 3, 4, 5 &
6 received 0.15mg/kg AlCl3 and 5mg/kg of composite tea
respectively. Twenty-four hours after last administration,
the animals were weighed, sedated with diethy-ether in a
chamber, and blood was collected. The testes were excised
and weighed. There were statistically significant
alterations in the percentage of seminiferous tubular and
seminiferous ductal diameter within the animals in all the
groups (p<0.05). Significant changes in sperm
parameters, hormone profiles and defective testicular
morphology in Groups 1, 3, 4 when compared to the
control group. However significant improvements were
noticed in Group 6 after administration of composite tea,
with restored sperm characteristics, restored hormonal
assessments and preserved testicular structures.
Conclusively, the ameliorating effect of the composite teas
were revealed on aluminum-induced toxicity of adult
Wistar rat.
Keywords :
Male Infertilty, Histomorphometry, Composite Teas, Aluminium, Testicular Toxicity
